Please use this identifier to cite or link to this item: https://doi.org/10.1007/s00125-011-2200-y
Title: Retinal vascular tortuosity in persons with diabetes and diabetic retinopathy
Authors: Sasongko, M.B.
Wong, T.Y. 
Nguyen, T.T.
Cheung, C.Y. 
Shaw, J.E.
Wang, J.J.
Keywords: Diabetes
Diabetes microvascular complications
Diabetic retinopathy
Retinal imaging
Retinal vascular tortuosity
Issue Date: Sep-2011
Citation: Sasongko, M.B., Wong, T.Y., Nguyen, T.T., Cheung, C.Y., Shaw, J.E., Wang, J.J. (2011-09). Retinal vascular tortuosity in persons with diabetes and diabetic retinopathy. Diabetologia 54 (9) : 2409-2416. ScholarBank@NUS Repository. https://doi.org/10.1007/s00125-011-2200-y
Abstract: Aim/hypothesis The aim of this hypothesis was to examine the association of retinal vessel tortuosity with diabetes and diabetic retinopathy (DR). Methods A clinic-based study of 327 participants (224 with diabetes and 103 non-diabetic controls) aged ≥18 years. DR was graded from fundus photographs according to the modified Airlie House Classification system and categorised into mild non-proliferative DR (NPDR), moderate NPDR and vision-threatening DR (VTDR). Retinal vessel tortuosity was measured from disc-centred retinal photographs. Measurements were taken, using a semiautomated computer program by a single grader, of arterioles and venules within 0.5 to 2 disc diameters away from the optic disc. Results There were 114 (44%) participants with DR. In the multivariate analysis, retinal arteriolar and venular tortuosity were increased in participants with diabetes without DR (mean difference 12.4×10 -5 and 13.3×10 -5, respectively; both p
Source Title: Diabetologia
URI: http://scholarbank.nus.edu.sg/handle/10635/109613
ISSN: 0012186X
DOI: 10.1007/s00125-011-2200-y
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