Please use this identifier to cite or link to this item: https://doi.org/10.2337/dc09-0719
Title: Retinal vascular fractal dimension and risk of early diabetic retinopathy: A prospective study of children and adolescents with type 1 diabetes
Authors: Shueh, W.L.
Cheung, N.
Wang, J.J.
Donaghue, K.C.
Liew, G.
Islam, F.M.A.
Jenkins, A.J.
Wong, T.Y. 
Issue Date: Nov-2009
Citation: Shueh, W.L., Cheung, N., Wang, J.J., Donaghue, K.C., Liew, G., Islam, F.M.A., Jenkins, A.J., Wong, T.Y. (2009-11). Retinal vascular fractal dimension and risk of early diabetic retinopathy: A prospective study of children and adolescents with type 1 diabetes. Diabetes Care 32 (11) : 2081-2083. ScholarBank@NUS Repository. https://doi.org/10.2337/dc09-0719
Abstract: OBJECTIVE - To examine the prospective association of retinal vascular fractal dimension with diabetic retinopathy risk in young people with type 1 diabetes. RESEARCH DESIGN AND METHODS - This was a hospital-based prospective study of 590 patients aged 12-20 years with type 1 diabetes free of retinopathy at baseline. All patients had seven-field retinal photographs taken of both eyes. Incident retinopathy was ascertained from retinal photographs taken at follow-up visits. Fractal dimension was measured from baseline photographs using a computer-based program following a standardized protocol. RESULTS - Over a mean ± SD follow-up period of 2.9 ± 2.0 years, 262 participants developed mild nonproliferative diabetic retinopathy (15.0 per 100 person-years). After adjusting for age, sex, diabetes duration, A1C, and other risk factors, we found no association between retinal vascular fractal dimension and incident retinopathy. CONCLUSIONS - Retinal vascular fractal dimension was not associated with incident early diabetic retinopathy in this sample of children and adolescents with type 1 diabetes. © 2009 by the American Diabetes Association.
Source Title: Diabetes Care
URI: http://scholarbank.nus.edu.sg/handle/10635/109609
ISSN: 01495992
DOI: 10.2337/dc09-0719
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