Please use this identifier to cite or link to this item: https://doi.org/10.1167/iovs.12-9986
DC FieldValue
dc.titleRelationship between intraocular pressure and angle configuration: An anterior segment OCT study
dc.contributor.authorChong, R.S.
dc.contributor.authorSakata, L.M.
dc.contributor.authorNarayanaswamy, A.K.
dc.contributor.authorHo, S.-W.
dc.contributor.authorHe, M.
dc.contributor.authorBaskaran, M.
dc.contributor.authorWong, T.Y.
dc.contributor.authorPerera, S.A.
dc.contributor.authorAung, T.
dc.date.accessioned2014-11-26T07:47:33Z
dc.date.available2014-11-26T07:47:33Z
dc.date.issued2013
dc.identifier.citationChong, R.S., Sakata, L.M., Narayanaswamy, A.K., Ho, S.-W., He, M., Baskaran, M., Wong, T.Y., Perera, S.A., Aung, T. (2013). Relationship between intraocular pressure and angle configuration: An anterior segment OCT study. Investigative Ophthalmology and Visual Science 54 (3) : 1650-1655. ScholarBank@NUS Repository. https://doi.org/10.1167/iovs.12-9986
dc.identifier.issn01460404
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109576
dc.description.abstractPurpose. To assess the relationship between intraocular pressure (IOP) and anterior chamber angle (ACA) configuration as assessed by gonioscopy and anterior segment optical coherence tomography (AS-OCT). Methods. A total of 2045 subjects aged 50 years and older, were recruited from a community clinic and underwent AS-OCT, Goldmann applanation tonometry, and gonioscopy. A quadrant was classified as closed on gonioscopy if the posterior trabecular meshwork could not be seen. A closed quadrant on AS-OCT was defined by the presence of any contact between the iris and angle wall anterior to the scleral spur. Customized software (Zhongshan Angle Assessment Program, Guangzhou, China) was used to measure AS-OCT parameters on AS-OCT scans, including anterior chamber depth, area, and volume; iris thickness (IT) and curvature; lens vault; angle opening distance; and trabecular-iris space area. IOP values were adjusted for age, sex, diabetes and hypertension status, body mass index, central corneal thickness, and presence of peripheral anterior synechiae. Results. Mean age of study subjects was 63.2 ± 8.0 years, 52.6% were female, and 89.4% were Chinese. Mean IOP was 14.8 ± 2.4 mm Hg (range 8-26). IOP (mean ± SE) increased with number of quadrants with gonioscopic angle closure (none: 14.6 ± 0.2; one: 14.7 ± 0.3; two: 15.0 ± 0.3; three: 15.0 ± 0.3; four: 15.6 ± 0.3 mm Hg; P < 0.001), and on AS-OCT (none: 14.7 ± 0.2; one: 15.0 ± 0.2; two: 14.8 ± 0.2; three: 15.1 ± 0.3; four: 16.0 ± 0.3 mm Hg; P < 0.001). IOP also increased in association with most of the ACA quantitative parameters measured on AS-OCT images, except for IT and lens vault. Conclusions. There was an association between the extent of angle closure, as assessed on AS-OCT and gonioscopy, with increasing IOP. © 2013 The Association for Research in Vision and Ophthalmology, Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1167/iovs.12-9986
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1167/iovs.12-9986
dc.description.sourcetitleInvestigative Ophthalmology and Visual Science
dc.description.volume54
dc.description.issue3
dc.description.page1650-1655
dc.description.codenIOVSD
dc.identifier.isiut000316942400010
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

18
checked on Nov 29, 2021

WEB OF SCIENCETM
Citations

17
checked on Nov 22, 2021

Page view(s)

96
checked on Dec 2, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.