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Title: Prevalence and characteristics of choroidal nevi in an asian vs white population
Authors: Ng, C.H.
Wang, J.J.
Mitchell, P.
Islam, F.M.A.
Wong, T.Y. 
Issue Date: Mar-2009
Citation: Ng, C.H., Wang, J.J., Mitchell, P., Islam, F.M.A., Wong, T.Y. (2009-03). Prevalence and characteristics of choroidal nevi in an asian vs white population. Archives of Ophthalmology 127 (3) : 314-319. ScholarBank@NUS Repository.
Abstract: Objective: To describe the prevalence and characteristics of choroidal nevi in an Asian population and compare this with findings from a white population. Methods: The Singapore Malay Eye Study (SiMES) examined a population-based, cross-sectional, age-stratified, random sample of 3280 Malay persons (78.7% participation rate) aged 40 to 80 years living in Singapore. Comprehensive examination of participants included bilateral retinal photography. Choroidal nevi were graded from photographs using the Blue Mountains Eye Study (BMES) protocol. Results: The person-specific prevalence of choroidal nevi was 1.4%, with 50 nevi found in 45 participants. This is lower than the 6.5% prevalence seen in white persons in the BMES. However, characteristics of nevi in Malay persons in the SiMES were similar to those of white persons in the BMES by size (SiMES, 1.27 mm; BMES, 1.25 mm; P = .35), shape (P = .58), color (P = .39), location within posterior pole or periphery (P = .30), and nevus margin proximity to the optic disc (P = .29). Features previously identified as indicating growth or malignant potential (including diameter >6 mm, posterior margin touching optic disc, orange pigment, pigment clumping, and retinal edema) were not found in this sample. Conclusion: Choroidal nevi were detected in 1.4% of Malay persons. There were no significant racial or ethnic differences in nevi characteristics between Malay and white persons. ©2009 American Medical Association. All rights reserved.
Source Title: Archives of Ophthalmology
ISSN: 00039950
DOI: 10.1001/archophthalmol.2008.625
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