Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.chroma.2013.11.025
DC FieldValue
dc.titlePreparation and characterization of 4-isopropylcalix[4]arene-capped (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy)-propylsilyl-appended silica particles as chiral stationary phase for high-performance liquid chromatography
dc.contributor.authorChelvi, S.K.T.
dc.contributor.authorZhao, J.
dc.contributor.authorChen, L.
dc.contributor.authorYan, S.
dc.contributor.authorYin, X.
dc.contributor.authorSun, J.
dc.contributor.authorYong, E.L.
dc.contributor.authorWei, Q.
dc.contributor.authorGong, Y.
dc.date.accessioned2014-11-26T07:47:02Z
dc.date.available2014-11-26T07:47:02Z
dc.date.issued2014-01-10
dc.identifier.citationChelvi, S.K.T., Zhao, J., Chen, L., Yan, S., Yin, X., Sun, J., Yong, E.L., Wei, Q., Gong, Y. (2014-01-10). Preparation and characterization of 4-isopropylcalix[4]arene-capped (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy)-propylsilyl-appended silica particles as chiral stationary phase for high-performance liquid chromatography. Journal of Chromatography A 1324 : 104-108. ScholarBank@NUS Repository. https://doi.org/10.1016/j.chroma.2013.11.025
dc.identifier.issn00219673
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109530
dc.description.abstractA new type of 4-isopropylcalix[4]arene-capped (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy)propylsilyl-appended silica particles (IPC4CD-HPS) has been prepared by treatment of bromoacetate-substituted (3-(2-O-β-cyclodextrin)-2-hydroxypropoxy)propylsilyl-appended silica particles (BACD-HPS) with 4-isopropylcalix[4]arene oxyanions in anhydrous N-methyl-2-pyrrolidone. The bonded silica IPC4CD-HPS has been successfully used as chiral stationary phase (CSP) in high-performance liquid chromatography (HPLC) for the first time. The synthetic stationary phase was characterized by means of elemental analysis and Fourier transform infrared spectroscopy. This new CSP has a chiral selector with two anchored functional moieties: 4-isopropylcalix[4]arene and β-cyclodextrin. The chromatographic performance of IPC4CD-HPS was investigated by separation of positional isomers of several disubstituted benzenes and enantiomers of some chiral drug compounds under reversed-phase conditions. The results showed that IPC4CD-HPS had excellent selectivity for the separation of aromatic positional isomers and enantiomers of chiral compounds due to the cooperative functioning of the anchored 4-isopropylcalix[4]arenes and β-cyclodextrins. © 2013 Elsevier B.V.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.chroma.2013.11.025
dc.sourceScopus
dc.subjectβ-Cyclodextrin
dc.subject4-Isopropylcalix[4]arene, Chiral separation
dc.subjectChiral stationary phase
dc.subjectHigh-performance liquid chromatography
dc.typeArticle
dc.contributor.departmentOBSTETRICS & GYNAECOLOGY
dc.description.doi10.1016/j.chroma.2013.11.025
dc.description.sourcetitleJournal of Chromatography A
dc.description.volume1324
dc.description.page104-108
dc.description.codenJCRAE
dc.identifier.isiut000330256100013
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

15
checked on Nov 26, 2020

WEB OF SCIENCETM
Citations

16
checked on Nov 26, 2020

Page view(s)

100
checked on Nov 28, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.