Please use this identifier to cite or link to this item: https://doi.org/10.1002/chir.20983
Title: Preparation and application of methylcalix[4]resorcinarene-bonded silica particles as chiral stationary phase in high-performance liquid chromatography
Authors: Tan, H.M.
Soh, S.F.
Zhao, J.
Yong, E.L.
Gong, Y. 
Keywords: C-methylcalix[4]resorcinarene
chiral separation
chiral stationary phase
high-performance liquid chromatography
Issue Date: 2011
Citation: Tan, H.M., Soh, S.F., Zhao, J., Yong, E.L., Gong, Y. (2011). Preparation and application of methylcalix[4]resorcinarene-bonded silica particles as chiral stationary phase in high-performance liquid chromatography. Chirality 23 (1 E) : E91-E97. ScholarBank@NUS Repository. https://doi.org/10.1002/chir.20983
Abstract: Two new types of methylcalix[4]resorcinarene-bonded stationary phases, (3-(C-methylcalix[4]resorcinarene)-2-hydroxypropoxy)-propylsilyl-appended silica particles (MCR-HPS) and bromoacetate-substituted MCR-HPS particles (BAMCR-HPS), have been synthesized and used as chiral stationary phases for high-performance liquid chromatography (HPLC) for the first time. The synthetic stationary phases are characterized by means of elemental analysis and Fourier-transform infrared spectroscopy. The chromatographic behavior of MCR-HPS and BAMCR-HPS was studied with several disubstituted benzenes and some chiral drug compounds under both normal phase and reversed-phase conditions. The results show that MCR-HPS has excellent selectivity for the separation of aromatic positional isomers and BAMCR-HPS exhibits excellent performance for separation of enantiomers of chiral compounds. © 2011 Wiley Periodicals, Inc.
Source Title: Chirality
URI: http://scholarbank.nus.edu.sg/handle/10635/109529
ISSN: 08990042
DOI: 10.1002/chir.20983
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

12
checked on Dec 6, 2019

WEB OF SCIENCETM
Citations

13
checked on Dec 6, 2019

Page view(s)

59
checked on Nov 29, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.