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|Title:||Huge proteins in the human proteome and their participation in hereditary diseases||Authors:||Sakharkar, M.K.
|Issue Date:||2006||Citation:||Sakharkar, M.K., Kangueane, P., Sakharkar, K.R., Zhong, Z. (2006). Huge proteins in the human proteome and their participation in hereditary diseases. In Silico Biology 6 (4) : 275-279. ScholarBank@NUS Repository.||Abstract:||Protein lengths vary considerably from a few to thousands of amino acids and length variations are documented to have multiple effects. A computational approach to investigate the functional impact of protein length variation in genetic disorders is presented. The genes for huge proteins are found to have more introns. Our analysis also shows greater involvement of huge proteins in hereditary diseases. © 2006 IOS Press. All rights reserved.||Source Title:||In Silico Biology||URI:||http://scholarbank.nus.edu.sg/handle/10635/109383||ISSN:||13866338|
|Appears in Collections:||Staff Publications|
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