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Title: Glycemic and blood pressure control in an Asian Malay population with diabetes and diabetic retinopathy
Authors: Huang, O.S.
Lamoureux, E.L.
Tay, W.T.
Tai, E.S.
Wang, J.J.
Wong, T.Y. 
Issue Date: Sep-2010
Citation: Huang, O.S., Lamoureux, E.L., Tay, W.T., Tai, E.S., Wang, J.J., Wong, T.Y. (2010-09). Glycemic and blood pressure control in an Asian Malay population with diabetes and diabetic retinopathy. Archives of Ophthalmology 128 (9) : 1185-1190. ScholarBank@NUS Repository.
Abstract: Objective: To examine the prevalence of and factors associated with suboptimal glycemic and blood pressure (BP) control in a Malay population with diabetes mellitus in Singapore. Methods: The Singapore Malay Eye Study was a population-based survey of 3280 Malay individuals (78.7% response rate) aged 40 to 80 years. Diabetes was defined as a nonfasting glucose level of 200 mg/dL or greater, use of diabetic medication, or physician diagnosis. Diabetic retinopathy (DR) was graded from retinal photographs using the modified Airlie House classification. Optimal control was defined as a hemoglobin A1c level of less than 7% and BP of 130/80 mm Hg or lower. Results: In participants with diabetes (n=768), only 26.9% had optimal glycemic and 13.4% optimal BP control, respectively. In those with DR (n=272), rates of optimal glycemic and BP control were even lower (17.4% and 10.3%, respectively). After adjusting for age, sex, socioeconomic status, and other factors, compared with participants with optimal glycemic control, those with suboptimal control were younger (P=.005), more likely to be unaware of their diabetes status (P < .001), and taking medication for diabetes (P < .001) and had higher levels of total cholesterol (P=.009) and DR (P < .001). After adjusting for similar risk factors, compared with participants with optimal BP control, those with suboptimal BP control were older (P=.006) and more likely to have higher total cholesterol levels (P=.002), BMIs (P=.04), and DR (P=.02). Conclusions: In this Asian Malay population with diabetes, more than three-quarters had poor glycemic and BP control. Strategies to improve awareness and implement evidence-based guidelines are needed to reduce the effect and burden of diabetic complications in Asia. ©2010 American Medical Association. All rights reserved.
Source Title: Archives of Ophthalmology
ISSN: 00039950
DOI: 10.1001/archophthalmol.2010.168
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