Please use this identifier to cite or link to this item:
https://doi.org/10.1017/S1041610213001129
Title: | Comparison of the Montreal Cognitive Assessment and the Mini-Mental State Examination in detecting multi-domain mild cognitive impairment in a Chinese sub-sample drawn from a population-based study | Authors: | Dong, Y. Yean Lee, W. Hilal, S. Saini, M. Wong, T.Y. Chen, C.L.-H. Venketasubramanian, N. Ikram, M.K. |
Keywords: | community mild cognitive impairment screening |
Issue Date: | Nov-2013 | Citation: | Dong, Y., Yean Lee, W., Hilal, S., Saini, M., Wong, T.Y., Chen, C.L.-H., Venketasubramanian, N., Ikram, M.K. (2013-11). Comparison of the Montreal Cognitive Assessment and the Mini-Mental State Examination in detecting multi-domain mild cognitive impairment in a Chinese sub-sample drawn from a population-based study. International Psychogeriatrics 25 (11) : 1831-1838. ScholarBank@NUS Repository. https://doi.org/10.1017/S1041610213001129 | Abstract: | ABSTRACT Background: We examined the discriminant validity of the Montreal Cognitive Assessment (MoCA) and the Mini-Mental State Examination (MMSE) in detecting multiple-domain mild cognitive impairment (md-MCI) in a Chinese sub-sample drawn from elderly population-based study. Methods: This study included Chinese participants from the Epidemiology of Dementia in Singapore (EDIS) study aged ≥ 60 years who underwent cognitive screening with the Abbreviated Mental Test and Progressive Forgetfulness Questionnaire. Screen-positive participants subsequently underwent MoCA, MMSE, and a comprehensive formal neuropsychological battery. MCI was defined by Petersen's criteria and further classified into single-domain MCI (sd-MCI) and md-MCI. Area under the receiver operating characteristic curve (AUC) with 95% confidence intervals (CIs) was computed for the MoCA and the MMSE in detecting md-MCI. Results: A total of 300 participants were recruited: 128 (42.7%) were diagnosed with no cognitive impairment (NCI), 47 (15.7%) with sd-MCI, and 83 (28.0%) with md-MCI. Forty-one participants were excluded, 7 (2.3%) had dementia, and 34 (11.3%) had only objective cognitive impairment without subjective complaints. Although the MoCA had a significantly larger AUC than the MMSE (0.94 (95% CI = 0.91-0.97) vs. 0.91 (95% CI = 0.86-0.95), p= 0.04), at optimal cut-off points, the MoCA (19/20) was equivalent to the MMSE (25/26) in detecting md-MCI (sensitivity: 0.80 vs. 0.87, specificity: 0.92 vs. 0.80). Conclusion: Both screening tests had good discriminant validity and can be used in detecting md-MCI in a sub-sample of Chinese drawn from a population-based study. © International Psychogeriatric Association 2013. | Source Title: | International Psychogeriatrics | URI: | http://scholarbank.nus.edu.sg/handle/10635/109261 | ISSN: | 10416102 | DOI: | 10.1017/S1041610213001129 |
Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.