Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.ophtha.2012.07.005
DC FieldValue
dc.titleClassification algorithms based on anterior segment optical coherence tomography measurements for detection of angle closure
dc.contributor.authorNongpiur, M.E.
dc.contributor.authorHaaland, B.A.
dc.contributor.authorFriedman, D.S.
dc.contributor.authorPerera, S.A.
dc.contributor.authorHe, M.
dc.contributor.authorFoo, L.-L.
dc.contributor.authorBaskaran, M.
dc.contributor.authorSakata, L.M.
dc.contributor.authorWong, T.Y.
dc.contributor.authorAung, T.
dc.date.accessioned2014-11-26T07:43:34Z
dc.date.available2014-11-26T07:43:34Z
dc.date.issued2013-01
dc.identifier.citationNongpiur, M.E., Haaland, B.A., Friedman, D.S., Perera, S.A., He, M., Foo, L.-L., Baskaran, M., Sakata, L.M., Wong, T.Y., Aung, T. (2013-01). Classification algorithms based on anterior segment optical coherence tomography measurements for detection of angle closure. Ophthalmology 120 (1) : 48-54. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ophtha.2012.07.005
dc.identifier.issn01616420
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109246
dc.description.abstractObjective: A recent study found that a combination of 6 anterior segment optical coherence tomography (ASOCT) parameters (anterior chamber area, volume, and width [ACA, ACV, ACW], lens vault [LV], iris thickness at 750 μm from the scleral spur, and iris cross-sectional area) explain >80% of the variability in angle width. The aim of this study was to evaluate classification algorithms based on ASOCT measurements for the detection of gonioscopic angle closure. Design: Cross-sectional study. Participants: We included 2047 subjects aged ≥50 years. Methods: Participants underwent gonioscopy and ASOCT (Carl Zeiss Meditec, Dublin, CA). Customized software (Zhongshan Angle Assessment Program, Guangzhou, China) was used to measure ASOCT parameters in horizontal ASOCT scans. Six classification algorithms were considered (stepwise logistic regression with Akaike information criterion, Random Forest, multivariate adaptive regression splines, support vector machine, naïve Bayes' classification, and recursive partitioning). The ASOCT-derived parameters were incorporated to generate point and interval estimates of the area under the receiver operating characteristic (AUC) curves for these algorithms using 10-fold cross-validation as well as 50:50 training and validation. Main Outcome Measures: We assessed ASOCT measurements and angle closure. Results: Data on 1368 subjects, including 295 (21.6%) subjects with gonioscopic angle closure were available for analysis. The mean (± standard deviation) age was 62.4±7.5 years and 54.8% were females. Angle closure subjects were older and had smaller ACW, ACA, and ACV; greater LV; and thicker irides (P95% of the time. Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article. © 2013 American Academy of Ophthalmology.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1016/j.ophtha.2012.07.005
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1016/j.ophtha.2012.07.005
dc.description.sourcetitleOphthalmology
dc.description.volume120
dc.description.issue1
dc.description.page48-54
dc.description.codenOPHTD
dc.identifier.isiut000313011700009
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

45
checked on Jul 26, 2021

WEB OF SCIENCETM
Citations

45
checked on Jul 26, 2021

Page view(s)

89
checked on Jul 13, 2021

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.