Please use this identifier to cite or link to this item: https://doi.org/10.1167/iovs.12-9787
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dc.titleAnterior chamber dimensions and posterior corneal arc length in Malay eyes: An anterior segment optical coherence tomography study
dc.contributor.authorTan, D.K.L.
dc.contributor.authorChong, W.
dc.contributor.authorTay, W.T.
dc.contributor.authorYuen, L.H.
dc.contributor.authorHe, M.
dc.contributor.authorAung, T.
dc.contributor.authorTan, D.T.H.
dc.contributor.authorWong, T.Y.
dc.contributor.authorMehta, J.S.
dc.date.accessioned2014-11-26T07:42:47Z
dc.date.available2014-11-26T07:42:47Z
dc.date.issued2012-07
dc.identifier.citationTan, D.K.L., Chong, W., Tay, W.T., Yuen, L.H., He, M., Aung, T., Tan, D.T.H., Wong, T.Y., Mehta, J.S. (2012-07). Anterior chamber dimensions and posterior corneal arc length in Malay eyes: An anterior segment optical coherence tomography study. Investigative Ophthalmology and Visual Science 53 (8) : 4860-4867. ScholarBank@NUS Repository. https://doi.org/10.1167/iovs.12-9787
dc.identifier.issn01460404
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109180
dc.description.abstractPURPOSE. We provided normative data of corneal and anterior segment dimensions, and a novel parameter, posterior corneal arc length (PCAL), in an adult Malay population. METHODS. The current analysis is a substudy of the Singapore Malay Eye Study (SiMES), a population-based, cross-sectional study of urban Malay adults aged 40 to 80. Subjects underwent ophthalmic and systemic examination, including imaging with anterior segment optical coherence tomography (AS-OCT). Ocular parameters subsequently were measured with the Zhongshan Assessment Program (ZAP), and included anterior chamber depth (ACD), central corneal thickness (CCT), anterior and posterior corneal curvature (ACC and PCC, respectively), and PCAL, which is a novel parameter defined as the arc-distance of the posterior corneal border between the scleral spurs. Age and sex-adjusted analyses, and multivariate analyses were performed to determine correlations of PCAL with other ocular and systemic components. RESULTS. We studied 237 subjects, among whom the mean age was 56.6 ± 10.4 years and 50.2% were women. Ocular parameters (mean ± SD) included central ACD 2.78 ± 0.34 mm, CCT 550.23 ± 37.12 mm, ACC 7.43 ± 0.37 mm, PCC 6.75 ± 0.37 mm, and PCAL 13.95 ± 0.51 mm. There was moderate correlation between PCAL and ACD (r 1/4 0.476, P < 0.001), but poor correlation with PCC (r 1/4 0.243, P < 0.001), ACC (r 1/4 0.251, P < 0.001), and systemic parameters, like age, body mass index (BMI), blood pressure, blood glucose levels, hemoglobin A1c (HbA1c), and refractive parameters. Multivariate analysis showed a significant association between PCAL and ACD (P < 0.001), PCC (P < 0.001), and height (P < 0.05). CONCLUSIONS. Our study, to our knowledge, provides the largest baseline anterior segment parameters in an adult Asian Malay population. PCAL correlated moderately with ACD. These data are applicable clinically for assessment and surgical management of patients requiring anterior segment or corneal surgery. © 2012 The Association for Research in Vision and Ophthalmology, Inc.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1167/iovs.12-9787
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentDUKE-NUS GRADUATE MEDICAL SCHOOL S'PORE
dc.contributor.departmentOPHTHALMOLOGY
dc.description.doi10.1167/iovs.12-9787
dc.description.sourcetitleInvestigative Ophthalmology and Visual Science
dc.description.volume53
dc.description.issue8
dc.description.page4860-4867
dc.description.codenIOVSD
dc.identifier.isiut000307096400063
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