Please use this identifier to cite or link to this item: https://doi.org/10.1302/0301-620X.95B5.31270
DC FieldValue
dc.titleBlood loss in spinal tumour surgery and surgery for metastatic spinal disease: A meta-analysis
dc.contributor.authorChen, Y.
dc.contributor.authorTai, B.C.
dc.contributor.authorNayak, D.
dc.contributor.authorKumar, N.
dc.contributor.authorChua, K.H.
dc.contributor.authorLim, J.W.
dc.contributor.authorGoy, R.W.L.
dc.contributor.authorWong, H.K.
dc.date.accessioned2014-11-26T05:05:41Z
dc.date.available2014-11-26T05:05:41Z
dc.date.issued2013-05
dc.identifier.citationChen, Y., Tai, B.C., Nayak, D., Kumar, N., Chua, K.H., Lim, J.W., Goy, R.W.L., Wong, H.K. (2013-05). Blood loss in spinal tumour surgery and surgery for metastatic spinal disease: A meta-analysis. Bone and Joint Journal 95 B (5) : 683-688. ScholarBank@NUS Repository. https://doi.org/10.1302/0301-620X.95B5.31270
dc.identifier.issn20494408
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/109108
dc.description.abstractThere is currently no consensus about the mean volume of blood lost during spinal tumour surgery and surgery for metastatic spinal disease. We conducted a systematic review of papers published in the English language between 31 January 1992 and 31 January 2012. Only papers that clearly presented blood loss data in spinal surgery for metastatic disease were included. The random effects model was used to obtain the pooled estimate of mean blood loss. We selected 18 papers, including six case series, ten retrospective reviews and two prospective studies. Altogether, there were 760 patients who had undergone spinal tumour surgery and surgery for metastatic spinal disease. The pooled estimate of peri-operative blood loss was 2180 ml (95% confidence interval 1805 to 2554) with catastrophic blood loss as high as 5000 ml, which is rare. Aside from two studies that reported large amounts of mean blood loss (> 5500 ml), the resulting funnel plot suggested an absence of publication bias. This was confirmed by Egger's test, which did not show any small-study effects (p = 0.119). However, there was strong evidence of heterogeneity between studies (I2 = 90%; p < 0.001). Spinal surgery for metastatic disease is associated with significant blood loss and the possibility of catastrophic blood loss. There is a need to establish standardised methods of calculating and reporting this blood loss. Analysis should include assessment by area of the spine, primary pathology and nature of surgery so that the amount of blood loss can be predicted. Consideration should be given to autotransfusion in these patients. © 2013 The British Editorial Society of Bone & Joint Surgery.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1302/0301-620X.95B5.31270
dc.sourceScopus
dc.typeReview
dc.contributor.departmentSAW SWEE HOCK SCHOOL OF PUBLIC HEALTH
dc.description.doi10.1302/0301-620X.95B5.31270
dc.description.sourcetitleBone and Joint Journal
dc.description.volume95 B
dc.description.issue5
dc.description.page683-688
dc.identifier.isiut000318348200019
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

30
checked on May 27, 2020

WEB OF SCIENCETM
Citations

27
checked on May 27, 2020

Page view(s)

96
checked on May 30, 2020

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.