Please use this identifier to cite or link to this item:
https://doi.org/10.1186/1471-2334-14-204
Title: | Respiratory viral pathogens among Singapore military servicemen 2009 - 2012: Epidemiology and clinical characteristics | Authors: | Tan, X.Q. Zhao, X. Lee, V.J. Loh, J.P. Tan, B.H. Koh, W.H.V. Ng, S.H. Chen, M.I.C. Cook, A.R. |
Keywords: | Epidemiology Influenza Influenza like-illness-ILI Respiratory infections Respiratory viruses Surveillance |
Issue Date: | 15-Apr-2014 | Citation: | Tan, X.Q., Zhao, X., Lee, V.J., Loh, J.P., Tan, B.H., Koh, W.H.V., Ng, S.H., Chen, M.I.C., Cook, A.R. (2014-04-15). Respiratory viral pathogens among Singapore military servicemen 2009 - 2012: Epidemiology and clinical characteristics. BMC Infectious Diseases 14 (1) : -. ScholarBank@NUS Repository. https://doi.org/10.1186/1471-2334-14-204 | Abstract: | Background: Few studies have comprehensively described tropical respiratory disease surveillance in military populations. There is also a lack of studies comparing clinical characteristics of the non-influenza pathogens with influenza and amongst themselves. Methods: From May 2009 through October 2012, 7733 consenting cases of febrile respiratory illness (FRI) (temperature [greater than or equal to]37.5degreesC with cough or sorethroat) and controls in the Singapore military had clinical data and nasal washes collected prospectively. Nasal washes underwent multiplex PCR, and the analysis was limited to viral mono-infections. Results: 49% of cases tested positive for at least one virus, of whom 10% had multiple infections. 53% of the FRI cases fulfilled the definition of influenza-like illness (ILI), of whom 52% were positive for at least one virus. The most frequent etiologies for mono-infections among FRI cases were Influenza A(H1N1)pdm09 (13%), Influenza B (13%) and coxsackevirus (9%). The sensitivity, specificity, positive predictive value and negative predictive value of ILI for influenza among FRI cases were 72%, 48%, 40% and 69% respectively. On logistic regression, there were marked differences in the prevalence of different symptoms and signs between viruses with fever more prevalent amongst influenza and adenovirus infections than other viruses. Conclusion: There are multiple viral etiologies for FRI and ILI with differing clinical symptoms in the Singapore military. Influenza and coxsackevirus were the most common etiology for FRI, while influenza and adenoviruses displayed the most febrile symptoms. Further studies should explore these differences and possible interventions. © 2014 Tan et al.; licensee BioMed Central Ltd. | Source Title: | BMC Infectious Diseases | URI: | http://scholarbank.nus.edu.sg/handle/10635/109036 | ISSN: | 14712334 | DOI: | 10.1186/1471-2334-14-204 |
Appears in Collections: | Staff Publications Elements |
Show full item record
Files in This Item:
File | Description | Size | Format | Access Settings | Version | |
---|---|---|---|---|---|---|
2014-respiratory_viral_pathogens_among_Singapore-pub.pdf | 1.01 MB | Adobe PDF | OPEN | Published | View/Download |
SCOPUSTM
Citations
16
checked on Jan 12, 2021
WEB OF SCIENCETM
Citations
16
checked on Jan 12, 2021
Page view(s)
234
checked on Jan 17, 2021
Download(s)
9
checked on Jan 17, 2021
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.