Please use this identifier to cite or link to this item:
https://doi.org/10.1371/journal.pmed.1001558
Title: | Global Mortality Estimates for the 2009 Influenza Pandemic from the GLaMOR Project: A Modeling Study | Authors: | Simonsen, L. Spreeuwenberg, P. Lustig, R. Taylor, R.J. Fleming, D.M. Kroneman, M. Van Kerkhove, M.D. Mounts, A.W. Paget, W.J. Echenique, H. Savy, V. Muscatello, D. MacIntyre, C.R. Dwyer, D.E. Azziz-Baumgartner, E. Homaira, N. Moura, F.E.A. Schuck, C. Akwar, H. Schanzer, D. Fuentes, R. Olea, A. Sotomayor, V. Feng, L. Yu, H. Mazick, A. Mølbak, K. Nielsen, J. Carrat, F. Lemaitre, M. Buchholz, U. Schweiger, B. Höhle, M. Vesenbeckh, S. Cowling, B. Leung, G. Tsang, T. Chuang, S.-K. Bromberg, M. Kaufman, Z. Sugaya, N. Oka Ezoe, K. Hayashi, S. Matsuda, M. Lopez-Gatell, H. Alpuche-Aranda, C. Noyola, D. Chowell, G. van Asten, L. Meijer, A. van den Wijngaard, K. van der Sande, M. Baker, M. Zhang, J. Benavides, J.G. Munayco, C. Laguna-Torres, A. Rabczenko, D. Wojtyniak, B. Park, S.-H. Lee, Y.-K. Zolotusca, L. Popovici, O. Popescu, R. Ang, L.W. Cutter, J. Lin, R. Ma, S. Chen, M. Lee, V.J. Prosenc, K. Socan, M. Cohen, C. Larrauri, A. de Mateo, S. Méndez, L.S. Sanz, C.D. Andrews, N. Green, H.K. Pebody, R. Saei, A. Shay, D. Viboud, C. |
Issue Date: | Nov-2013 | Citation: | Simonsen, L., Spreeuwenberg, P., Lustig, R., Taylor, R.J., Fleming, D.M., Kroneman, M., Van Kerkhove, M.D., Mounts, A.W., Paget, W.J., Echenique, H., Savy, V., Muscatello, D., MacIntyre, C.R., Dwyer, D.E., Azziz-Baumgartner, E., Homaira, N., Moura, F.E.A., Schuck, C., Akwar, H., Schanzer, D., Fuentes, R., Olea, A., Sotomayor, V., Feng, L., Yu, H., Mazick, A., Mølbak, K., Nielsen, J., Carrat, F., Lemaitre, M., Buchholz, U., Schweiger, B., Höhle, M., Vesenbeckh, S., Cowling, B., Leung, G., Tsang, T., Chuang, S.-K., Bromberg, M., Kaufman, Z., Sugaya, N., Oka Ezoe, K., Hayashi, S., Matsuda, M., Lopez-Gatell, H., Alpuche-Aranda, C., Noyola, D., Chowell, G., van Asten, L., Meijer, A., van den Wijngaard, K., van der Sande, M., Baker, M., Zhang, J., Benavides, J.G., Munayco, C., Laguna-Torres, A., Rabczenko, D., Wojtyniak, B., Park, S.-H., Lee, Y.-K., Zolotusca, L., Popovici, O., Popescu, R., Ang, L.W., Cutter, J., Lin, R., Ma, S., Chen, M., Lee, V.J., Prosenc, K., Socan, M., Cohen, C., Larrauri, A., de Mateo, S., Méndez, L.S., Sanz, C.D., Andrews, N., Green, H.K., Pebody, R., Saei, A., Shay, D., Viboud, C. (2013-11). Global Mortality Estimates for the 2009 Influenza Pandemic from the GLaMOR Project: A Modeling Study. PLoS Medicine 10 (11) : -. ScholarBank@NUS Repository. https://doi.org/10.1371/journal.pmed.1001558 | Abstract: | Background:Assessing the mortality impact of the 2009 influenza A H1N1 virus (H1N1pdm09) is essential for optimizing public health responses to future pandemics. The World Health Organization reported 18,631 laboratory-confirmed pandemic deaths, but the total pandemic mortality burden was substantially higher. We estimated the 2009 pandemic mortality burden through statistical modeling of mortality data from multiple countries.Methods and Findings:We obtained weekly virology and underlying cause-of-death mortality time series for 2005-2009 for 20 countries covering ∼35% of the world population. We applied a multivariate linear regression model to estimate pandemic respiratory mortality in each collaborating country. We then used these results plus ten country indicators in a multiple imputation model to project the mortality burden in all world countries. Between 123,000 and 203,000 pandemic respiratory deaths were estimated globally for the last 9 mo of 2009. The majority (62%-85%) were attributed to persons under 65 y of age. We observed a striking regional heterogeneity, with almost 20-fold higher mortality in some countries in the Americas than in Europe. The model attributed 148,000-249,000 respiratory deaths to influenza in an average pre-pandemic season, with only 19% in persons | Source Title: | PLoS Medicine | URI: | http://scholarbank.nus.edu.sg/handle/10635/108950 | ISSN: | 15491277 | DOI: | 10.1371/journal.pmed.1001558 |
Appears in Collections: | Staff Publications Elements |
Show full item record
Files in This Item:
File | Description | Size | Format | Access Settings | Version | |
---|---|---|---|---|---|---|
2013-Global_Mortality_Estimates_for_the-published.PDF | 1.75 MB | Adobe PDF | OPEN | Published | View/Download |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.