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Title: Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: A systematicreview and a dose-response meta-analysis
Authors: Ding, M.
Bhupathiraju, S.N.
Chen, M.
Van Dam, R.M. 
Hu, F.B.
Issue Date: Feb-2014
Citation: Ding, M., Bhupathiraju, S.N., Chen, M., Van Dam, R.M., Hu, F.B. (2014-02). Caffeinated and decaffeinated coffee consumption and risk of type 2 diabetes: A systematicreview and a dose-response meta-analysis. Diabetes Care 37 (2) : 569-586. ScholarBank@NUS Repository.
Abstract: OBJECTIVE Previous meta-analyses identified an inverse association of coffee consumption with the risk of type 2 diabetes. However, an updated meta-analysis is needed because new studies comparing the trends of association for caffeinated and decaffeinated coffee have since been published. RESEARCH DESIGN AND METHODS PubMed and Embase were searched for cohort or nested case-control studies that assessed the relationship of coffee consumption and risk of type 2 diabetes from 1966 to February 2013. Arestricted cubic spline random-effects modelwas used. RESULTS Twenty-eight prospective studies were included in the analysis, with 1,109,272 study participants and 45,335 cases of type 2 diabetes. The follow-up duration ranged from 10 months to 20 years. Compared with no or rare coffee consumption, the relative risk (RR; 95% CI) for diabetes was 0.92 (0.90-0.94), 0.85 (0.82- 0.88), 0.79 (0.75-0.83), 0.75 (0.71-0.80), 0.71 (0.65-0.76), and 0.67 (0.61-0.74) for 1-6 cups/day, respectively. The RR of diabetes for a 1 cup/day increase was 0.91 (0.89-0.94) for caffeinated coffee consumption and 0.94 (0.91-0.98) for decaffeinated coffee consumption (P for difference = 0.17). CONCLUSIONS Coffee consumption was inversely associated with the risk of type 2 diabetes in a dose-response manner. Both caffeinated and decaffeinated coffeewas associated with reduced diabetes risk. © 2014 by the American Diabetes Association.
Source Title: Diabetes Care
ISSN: 01495992
DOI: 10.2337/dc13-1203
Appears in Collections:Staff Publications

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