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Title: Vascular risk factors in glaucoma: A review
Authors: Yanagi, M.
Kawasaki, R.
Wang, J.J.
Wong, T.Y. 
Crowston, J.
Kiuchi, Y.
Keywords: Ocular blood flow
Ocular perfusion pressure
Retinal ganglion cell
Retinal vascular calibre
Issue Date: Apr-2011
Citation: Yanagi, M., Kawasaki, R., Wang, J.J., Wong, T.Y., Crowston, J., Kiuchi, Y. (2011-04). Vascular risk factors in glaucoma: A review. Clinical and Experimental Ophthalmology 39 (3) : 252-258. ScholarBank@NUS Repository.
Abstract: Glaucoma, one of the major causes of blindness in the world, is a progressive optic neuropathy. Elevated intraocular pressure is a well-known major risk factor for glaucoma. In addition, there is growing evidence that vascular factors may play a role in glaucoma pathogenesis. Systemic (e.g. hypertension, diabetes) and ocular vascular factors (e.g. ocular blood flow, ocular perfusion pressure) have been assessed for associations with glaucoma. However, direct and convincing evidence for primary mechanisms of glaucoma is still lacking. The aim of this review is to summarize the evidence implicating vascular factors in the pathogenesis of glaucoma, with particular emphasis on the role of ocular blood flow and ocular circulation as risk factors for primary open angle glaucoma. © 2011 The Authors. Clinical and Experimental Ophthalmology © 2011 Royal Australian and New Zealand College of Ophthalmologists.
Source Title: Clinical and Experimental Ophthalmology
ISSN: 14426404
DOI: 10.1111/j.1442-9071.2010.02455.x
Appears in Collections:Staff Publications

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