Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1469-8986.2010.01011.x
Title: Ethnicity, gender, genotype, and anger as related to nocturnal dipping
Authors: Bishop, G.D.
Ng, D.P.K. 
Ngau, F.
Nurbaya, S.
Keywords: 5-HTTLPR
Anger
Ethnicity
Nocturnal dipping
Plasticity
Singapore
Issue Date: Nov-2010
Citation: Bishop, G.D., Ng, D.P.K., Ngau, F., Nurbaya, S. (2010-11). Ethnicity, gender, genotype, and anger as related to nocturnal dipping. Psychophysiology 47 (6) : 1094-1101. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1469-8986.2010.01011.x
Abstract: Bishop, Pek, and Ngau (2005) found a significant interaction in Singapore between anger and nocturnal dipping among Indians but not Chinese and Malays. The current study examines the role of 5-HTTLPR genotype in this relationship. Two hundred thirty-one undergraduates participated in up to 4 days of 24-h ambulatory monitoring, completed the State-Trait Anger Expression Inventory, and provided blood samples for genotyping of 5-HTTLPR. Results indicated individuals with two copies of the short allele (SS) showed reduced dipping when they were high in Outward Anger (OA) but increased dipping when they were low in OA. Further, for Indian men only, dipping was reduced for individuals having the SS genotype when they were low on Anger In and increased when they were high on Anger In. These data provide further evidence for the role of 5-HTTLPR in cardiovascular risk as well as ethnic differences in the 5-HTTLPR-phenotype relationship. They also provide further evidence for 5-HTTLPR as a "plasticity gene." © 2010 Society for Psychophysiological Research.
Source Title: Psychophysiology
URI: http://scholarbank.nus.edu.sg/handle/10635/108374
ISSN: 00485772
DOI: 10.1111/j.1469-8986.2010.01011.x
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