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|Title:||BMI and diabetes risk in Singaporean Chinese||Authors:||Odegaard, A.O.
|Issue Date:||Jun-2009||Citation:||Odegaard, A.O., Koh, W.-P., Vazquez, G., Arakawa, K., Lee, H.-P., Yu, M.C., Pereira, M.A. (2009-06). BMI and diabetes risk in Singaporean Chinese. Diabetes Care 32 (6) : 1104-1106. ScholarBank@NUS Repository. https://doi.org/10.2337/dc08-1674||Abstract:||OBJECTIVE - Increased BMI is a robust risk factor for type 2 diabetes. Paradoxically, South Asians have relatively low BMIs despite their high prevalence of type 2 diabetes. We examined the association between BMI and incident type 2 diabetes because detailed prospective cohort data on this topic in Asians are scarce. RESEARCH DESIGN AND METHODS - This study was a prospective analysis of 37,091 men and women aged 45-74 years in the Singapore Chinese Health Study, using Cox regression analysis. RESULTS - Risk of incident type 2 diabetes significantly increased beginning with BMIs 18.5-23.0 kg/m2 (relative risk 2.47 [95% CI 1.75-3.48]) and continued in a monotonic fashion across the spectrum of BMI. Results were stronger for younger than for older adults. CONCLUSIONS - BMIs considered lean and normal in Singaporean Chinese are strongly associated with increased risk of incident type 2 diabetes. This association weakened with advanced age but remained significant. © 2009 by the American Diabetes Association.||Source Title:||Diabetes Care||URI:||http://scholarbank.nus.edu.sg/handle/10635/108277||ISSN:||01495992||DOI:||10.2337/dc08-1674|
|Appears in Collections:||Staff Publications|
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