Please use this identifier to cite or link to this item: https://doi.org/10.1093/bioinformatics/btr007
Title: A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies
Authors: Ong, R.T.-H. 
Liu, X.
Poh, W.-T. 
Sim, X. 
Chia, K.-S. 
Teo, Y.-Y. 
Issue Date: Mar-2011
Citation: Ong, R.T.-H., Liu, X., Poh, W.-T., Sim, X., Chia, K.-S., Teo, Y.-Y. (2011-03). A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies. Bioinformatics 27 (6) : 822-828. ScholarBank@NUS Repository. https://doi.org/10.1093/bioinformatics/btr007
Abstract: Motivation: Methods for detecting positive selection relied on finding evidence of long haplotypes to identify candidate regions under selection. However, these methods generally do not identify the length and form of the selected haplotype. Results: We present HapFinder, a method which can find the common longest haplotype under three different settings from a database, which is relevant in the analysis of positive selection in population genetics and also in medical genetics for finding the likely haplotype form carrying the causal allele at the functional polymorphism. © The Author 2011. Published by Oxford University Press. All rights reserved.
Source Title: Bioinformatics
URI: http://scholarbank.nus.edu.sg/handle/10635/108233
ISSN: 13674803
DOI: 10.1093/bioinformatics/btr007
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

4
checked on Nov 17, 2019

WEB OF SCIENCETM
Citations

4
checked on Nov 8, 2019

Page view(s)

119
checked on Nov 9, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.