Please use this identifier to cite or link to this item:
|Title:||A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies||Authors:||Ong, R.T.-H.
|Issue Date:||Mar-2011||Citation:||Ong, R.T.-H., Liu, X., Poh, W.-T., Sim, X., Chia, K.-S., Teo, Y.-Y. (2011-03). A method for identifying haplotypes carrying the causative allele in positive natural selection and genome-wide association studies. Bioinformatics 27 (6) : 822-828. ScholarBank@NUS Repository. https://doi.org/10.1093/bioinformatics/btr007||Abstract:||Motivation: Methods for detecting positive selection relied on finding evidence of long haplotypes to identify candidate regions under selection. However, these methods generally do not identify the length and form of the selected haplotype. Results: We present HapFinder, a method which can find the common longest haplotype under three different settings from a database, which is relevant in the analysis of positive selection in population genetics and also in medical genetics for finding the likely haplotype form carrying the causal allele at the functional polymorphism. © The Author 2011. Published by Oxford University Press. All rights reserved.||Source Title:||Bioinformatics||URI:||http://scholarbank.nus.edu.sg/handle/10635/108233||ISSN:||13674803||DOI:||10.1093/bioinformatics/btr007|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Oct 21, 2019
WEB OF SCIENCETM
checked on Oct 14, 2019
checked on Oct 11, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.