Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/108081
DC Field | Value | |
---|---|---|
dc.title | Population genetics of the angiotensin-converting enzyme in Chinese | |
dc.contributor.author | Lee, E.J.D. | |
dc.date.accessioned | 2014-11-20T05:58:41Z | |
dc.date.available | 2014-11-20T05:58:41Z | |
dc.date.issued | 1994 | |
dc.identifier.citation | Lee, E.J.D. (1994). Population genetics of the angiotensin-converting enzyme in Chinese. British Journal of Clinical Pharmacology 37 (2) : 212-214. ScholarBank@NUS Repository. | |
dc.identifier.issn | 03065251 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/108081 | |
dc.description.abstract | A genetic polymorphism exists for the angiotensin-converting enzyme (ACE) gene which accounts for 44% of the variance of circulating ACE activity in a normal Caucasian population. The presence or absence of a 250 bp fragment in intron 16 of the gene serves as a marker for this polymorphism. One hundred and eighty-nine normal Chinese subjects were genotyped and phenotyped for this ACE polymorphism. The frequencies of the deletion and insertion alleles among Chinese are 0.3 and 0.7 respectively, indicating a much higher prevalence of the insertion allele than had been reported among Caucasians. | |
dc.source | Scopus | |
dc.type | Article | |
dc.contributor.department | PHARMACOLOGY | |
dc.description.sourcetitle | British Journal of Clinical Pharmacology | |
dc.description.volume | 37 | |
dc.description.issue | 2 | |
dc.description.page | 212-214 | |
dc.description.coden | BCPHB | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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