Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/108056
DC Field | Value | |
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dc.title | Differences in anxiety-related behavior between apolipoprotein E-deficient C57BL/6 and wild type C57BL/6 mice | |
dc.contributor.author | McLachlan, C.S. | |
dc.contributor.author | Yi Xing Soh, C. | |
dc.date.accessioned | 2014-11-20T05:58:24Z | |
dc.date.available | 2014-11-20T05:58:24Z | |
dc.date.issued | 2005 | |
dc.identifier.citation | McLachlan, C.S.,Yi Xing Soh, C. (2005). Differences in anxiety-related behavior between apolipoprotein E-deficient C57BL/6 and wild type C57BL/6 mice. Physiological Research 54 (6) : 701-704. ScholarBank@NUS Repository. | |
dc.identifier.issn | 08628408 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/108056 | |
dc.description.abstract | The influence of ApoE gene deletion on the anxiety state has not been previously investigated. The elevated plus maze was used in this study to determine differences in anxiety-related behavior between apoE-deficient and wild type C57BL/6 mice. The apoE-deficient mice demonstrated less anxiety on the elevated plus maze by spending more time in the open arms of the elevated plus maze compared to wild type mice (p<0.001). Additionally, female apoE-deficient mice visited the open arm of the maze more often than their apoE-deficient male counterpart (p<0.05). The anxiety state and/or sex are possible variables to be considered when designing physiological and/or behavioral studies involving mice that are apoE-deficient. © 2005 Institute of Physiology, Academy of Sciences of the Czech Republic. | |
dc.source | Scopus | |
dc.subject | Anxiety | |
dc.subject | Apolipoprotein E | |
dc.subject | Elevated plus maze | |
dc.subject | Mice | |
dc.type | Article | |
dc.contributor.department | PHARMACOLOGY | |
dc.description.sourcetitle | Physiological Research | |
dc.description.volume | 54 | |
dc.description.issue | 6 | |
dc.description.page | 701-704 | |
dc.description.coden | PHRSE | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
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