Please use this identifier to cite or link to this item: https://doi.org/10.1016/j.chroma.2009.12.050
Title: Pressurized hot water extraction (PHWE)
Authors: Teo, C.C.
Tan, S.N.
Yong, J.W.H.
Hew, C.S.
Ong, E.S. 
Keywords: Green extraction
Metabolites
Pilot-scale
Pressurized hot water extraction
Scaled-up
Temperature
Issue Date: Apr-2010
Citation: Teo, C.C., Tan, S.N., Yong, J.W.H., Hew, C.S., Ong, E.S. (2010-04). Pressurized hot water extraction (PHWE). Journal of Chromatography A 1217 (16) : 2484-2494. ScholarBank@NUS Repository. https://doi.org/10.1016/j.chroma.2009.12.050
Abstract: Pressurized hot water extraction (PHWE) has become a popular green extraction method for different classes of compounds present in numerous kinds of matrices such as environmental, food and botanical samples. PHWE is also used in sample preparation to extract organic contaminants from foodstuff for food safety analysis and soils/sediments for environmental monitoring purposes. The main parameters which influence its extraction efficiency are namely the temperature, extraction time, flow rates and addition of modifiers/additives. Among these different parameters studied, temperature is described as the most important one. It is reported that the extraction of certain compounds is rather dependent on pressurized water with different applied temperature. Thus, the stability and reduced solubilities of certain compounds at elevated temperatures are highlighted in this review. With some modifications, a scaled-up PHWE could extract a higher amount of desirable compounds from solid and powdered samples such as plant and food materials. The PHWE extracts from plants are rich in chemical compounds or metabolites which can be a potential lead for drug discovery or development of disease-resistant food crops. © 2009 Elsevier B.V.
Source Title: Journal of Chromatography A
URI: http://scholarbank.nus.edu.sg/handle/10635/107964
ISSN: 00219673
DOI: 10.1016/j.chroma.2009.12.050
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