Please use this identifier to cite or link to this item:
|Title:||The relationship between nasopharyngeal carcinoma tumor volume and TNM T-classification: A quantitative analysis||Authors:||Zhou, J.-Y.
|Issue Date:||Feb-2007||Citation:||Zhou, J.-Y., Chong, V.F.H., Khoo, J.B.K., Chan, K.-L., Huang, J. (2007-02). The relationship between nasopharyngeal carcinoma tumor volume and TNM T-classification: A quantitative analysis. European Archives of Oto-Rhino-Laryngology 264 (2) : 169-174. ScholarBank@NUS Repository. https://doi.org/10.1007/s00405-006-0163-2||Abstract:||Recent findings show that tumor volume is a significant prognostic factor for the treatment of nasopharyngeal carcinoma (NPC). The inclusion of tumor volume as an additional prognostic factor in the UICC TNM classification system was suggested; however, how tumor volume could possibly be incorporated is still unexplored. In this paper, we report a quantitative analysis on the relationship between NPC tumor volume and T-classification, using the data from 206 NPC patients. By T-classification and semi-automatic tumor volume measurement, the difference in tumor volumes among the various TNM T-classification groups was examined. In addition, a statistics-based analysis scheme, which used the T-classification as the "gold standard", was proposed to classify NPC tumors into volume-based groups to explore the possible links. The results show that NPC tumor volume has positive correlation with advancing T-classification groups and significant difference existed in the distribution of T-classification among various volume-based groups (P < 0.001). By the proposed statistical scheme, tumor volume could be included as an additional prognostic factor in the TNM framework, following validation studies. © 2006 Springer-Verlag.||Source Title:||European Archives of Oto-Rhino-Laryngology||URI:||http://scholarbank.nus.edu.sg/handle/10635/107919||ISSN:||09374477||DOI:||10.1007/s00405-006-0163-2|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Oct 12, 2019
WEB OF SCIENCETM
checked on Jul 9, 2019
checked on Oct 11, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.