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|Title:||Cloning and characterization of mouse glial cell line-derived neurotrophic growth factor (GDNF)||Authors:||Wang, F.-J.
Gene cloning and expression 5 growth factor
|Issue Date:||1998||Citation:||Wang, F.-J.,Zhao, J.,Too, H.P. (1998). Cloning and characterization of mouse glial cell line-derived neurotrophic growth factor (GDNF). Acta Biochimica et Biophysica Sinica 30 (4) : 380-381. ScholarBank@NUS Repository.||Abstract:||We have cloned two unique forms of glial cell line-derived neurotrophic growth factor transcripts (GDNF-α and GDNF-β) from adult mouse brain. The GDNF-α form is similar to GDNF-α except for a 78 bp deletion in the ORF. The deduced amino acid sequences of the mouse GDNF-α are highly homologous to those of rat and human GDNF. Reverse-transcription PCR from various mouse tissues snowed extensive expression of both forms of GDNF. GDNF-α is coded by at least two distinct exons. The 3′-UTR is entirely encoded in a single exon.||Source Title:||Acta Biochimica et Biophysica Sinica||URI:||http://scholarbank.nus.edu.sg/handle/10635/107772||ISSN:||05829879|
|Appears in Collections:||Staff Publications|
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