Please use this identifier to cite or link to this item: https://doi.org/10.1038/nrd2960
Title: A pre-emptive strike against malaria's stealthy hepatic forms
Authors: Mazier, D.
Rénia, L. 
Snounou, G. 
Issue Date: 2009
Citation: Mazier, D., Rénia, L., Snounou, G. (2009). A pre-emptive strike against malaria's stealthy hepatic forms. Nature Reviews Drug Discovery 8 (11) : 854-864. ScholarBank@NUS Repository. https://doi.org/10.1038/nrd2960
Abstract: Almost all the drugs that are widely used today against Plasmodium spp., the causative agent of malaria, target the asexual blood stages of the parasite. Widespread drug resistance severely restricts our ability to control malaria and makes it necessary to seek novel antimalarial compounds. Here, we advocate the development of true causal chemoprophylactic drugs that will fully inhibit the obligate short-lived hepatic forms that precede blood infections. Such drugs will prevent pathology and interrupt transmission, and could therefore have an important role in the control of malaria and its eventual eradication.
Source Title: Nature Reviews Drug Discovery
URI: http://scholarbank.nus.edu.sg/handle/10635/107630
ISSN: 14741776
DOI: 10.1038/nrd2960
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

74
checked on Oct 16, 2019

WEB OF SCIENCETM
Citations

65
checked on Oct 9, 2019

Page view(s)

83
checked on Oct 11, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.