Please use this identifier to cite or link to this item: https://doi.org/10.1039/b404964k
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dc.titleCarboxyl group (-CO2H) functionalized ferrimagnetic iron oxide nanoparticles for potential bio-applications
dc.contributor.authorYu, S.
dc.contributor.authorChow, C.M.
dc.date.accessioned2014-10-29T08:37:44Z
dc.date.available2014-10-29T08:37:44Z
dc.date.issued2004-09-21
dc.identifier.citationYu, S., Chow, C.M. (2004-09-21). Carboxyl group (-CO2H) functionalized ferrimagnetic iron oxide nanoparticles for potential bio-applications. Journal of Materials Chemistry 14 (18) : 2781-2786. ScholarBank@NUS Repository. https://doi.org/10.1039/b404964k
dc.identifier.issn09599428
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/106975
dc.description.abstractA new approach to prepare surface-functionalized magnetic nanoparticles by synthesis of poly(methacrylic acid) (PMAA) coated maghemite nanoparticles in aqueous solution is reported. Maghemite (γ-Fe2O3) nanoparticles with an average diameter of 8 ± 2 nm were fabricated and subsequently coated with PMAA by emulsion polymerization. The FTIR study and thermal analysis confirmed the chemical adsorption of methacrylic acid on the maghemite nanoparticle surface, and suggested a symmetrical carboxylate bonding. The free carboxyl group of PMAA, which was verified by FTIR spectroscopy and zeta potential measurement, provided the site for immobilization of foreign molecules. The PMAA coated maghemite nanoparticles were demonstrated as potential magnetically targeted drug carriers by adsorbing an anti-cancer drug (carboplatin) via the ion-dipole interaction between CO2 - of PMAA and carboplatin.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1039/b404964k
dc.sourceScopus
dc.typeArticle
dc.contributor.departmentMATERIALS SCIENCE
dc.description.doi10.1039/b404964k
dc.description.sourcetitleJournal of Materials Chemistry
dc.description.volume14
dc.description.issue18
dc.description.page2781-2786
dc.description.codenJMACE
dc.identifier.isiut000223760200014
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