Please use this identifier to cite or link to this item: https://doi.org/10.3109/1061186X.2013.805335
Title: Novel engineered systems for oral, mucosal and transdermal drug delivery
Authors: Li, H. 
Yu, Y.
Faraji Dana, S.
Li, B.
Lee, C.-Y.
Kang, L. 
Keywords: Buccal
Drug delivery
Microfabrication
Mucosal
Nasal
Ocular
Oral
Pulmonary
Rectal
Transdermal
Vaginal
Issue Date: Aug-2013
Citation: Li, H., Yu, Y., Faraji Dana, S., Li, B., Lee, C.-Y., Kang, L. (2013-08). Novel engineered systems for oral, mucosal and transdermal drug delivery. Journal of Drug Targeting 21 (7) : 611-629. ScholarBank@NUS Repository. https://doi.org/10.3109/1061186X.2013.805335
Abstract: Technological advances in drug discovery have resulted in increasing number of molecules including proteins and peptides as drug candidates. However, how to deliver drugs with satisfactory therapeutic effect, minimal side effects and increased patient compliance is a question posted before researchers, especially for those drugs with poor solubility, large molecular weight or instability. Microfabrication technology, polymer science and bioconjugate chemistry combine to address these problems and generate a number of novel engineered drug delivery systems. Injection routes usually have poor patient compliance due to their invasive nature and potential safety concerns over needle reuse. The alternative non-invasive routes, such as oral, mucosal (pulmonary, nasal, ocular, buccal, rectal, vaginal), and transdermal drug delivery have thus attracted many attentions. Here, we review the applications of the novel engineered systems for oral, mucosal and transdermal drug delivery. © 2013 Informa UK Ltd.
Source Title: Journal of Drug Targeting
URI: http://scholarbank.nus.edu.sg/handle/10635/106690
ISSN: 1061186X
DOI: 10.3109/1061186X.2013.805335
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