Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/106646
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dc.titleDrug utilization review of risperidone for outpatients in a tertiary referral hospital in Singapore
dc.contributor.authorLuo, N.
dc.contributor.authorKoh, Y.
dc.contributor.authorTan, C.H.
dc.contributor.authorKua, E.H.
dc.contributor.authorLi, S.C.
dc.date.accessioned2014-10-29T02:03:08Z
dc.date.available2014-10-29T02:03:08Z
dc.date.issued2004-06
dc.identifier.citationLuo, N., Koh, Y., Tan, C.H., Kua, E.H., Li, S.C. (2004-06). Drug utilization review of risperidone for outpatients in a tertiary referral hospital in Singapore. Human Psychopharmacology 19 (4) : 259-264. ScholarBank@NUS Repository.
dc.identifier.issn08856222
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/106646
dc.description.abstractBackground. Risperidone has been used in Singapore for schizophrenia since 1996. However, little information is available on its utilization pattern. Objective. To examine the risperidone utilization pattern in the Psychiatric Outpatient Clinic of the National University Hospital. Method. Medical records of all outpatients with schizophrenia prescribed with risperidone from 1 September1999 to 31 August 2000 were reviewed. Results. A total of 417 risperidone prescriptions were dispensed for 130 outpatients (50 male, 80 female) during the study period. The mean ± SD daily doses for prescriptions and for patients were 2.3 ± 1.3 mg and 2.1 ± 1.1 mg, respectively. Among these patients, 28 (21.5%) received at least one concomitant conventional antipsychotic and 71 (54.6%) received a concomitant anti-Parkinsonian agent. Logistic regression analysis suggested that a higher risperidone dose was associated with the greater probability of anti-Parkinsonian agent usage. Conclusions. The mean risperidone dose during the study period was towards the lower end of recommendation for schizophrenia. Further study is warranted to confirm and explain the pattern of low-dose risperidone, and the high use of concomitant conventional antipsychotics and anti-Parkinsonian agents in Singapore. Elucidation of these would provide a valuable insight for the management of Asian patients with schizophrenia using risperidone. However, the current data indicate that the practice of using a lower dose of risperidone could represent better affordability and an improved cost-effectiveness ratio of risperidone compared with conventional antipsychotics in Asian patients. Copyright © 2004 John Wiley & Sons, Ltd.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/hup.585
dc.sourceScopus
dc.subjectAsian
dc.subjectDrug utilization
dc.subjectRisperidone
dc.subjectSchizophrenia
dc.typeReview
dc.contributor.departmentPHARMACY
dc.description.sourcetitleHuman Psychopharmacology
dc.description.volume19
dc.description.issue4
dc.description.page259-264
dc.description.codenHUPSE
dc.identifier.isiut000222206800006
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