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Title: Nanosphere templated optical fiber for in-vivo SERS sensing applications
Authors: Dinish, U.S.
Fu, C.Y.
Goh, D.
Olivo, M. 
Keywords: Biosensing
Optical fiber
Polystyrene nanospheres
Remote sensing
Surface Enhanced Raman Scattering
Issue Date: 2010
Citation: Dinish, U.S.,Fu, C.Y.,Goh, D.,Olivo, M. (2010). Nanosphere templated optical fiber for in-vivo SERS sensing applications. 2010 Photonics Global Conference, PGC 2010 : -. ScholarBank@NUS Repository.
Abstract: We report a new class of Surface Enhanced Raman Scattering (SERS)-optical fiber sensing platform with hexagonally packed polystyrene (PS) nanospheres coated with silver at the distal end of the fiber with signal collected in a back scattering geometry. As a proof of concept, we fabricated the SERS-active substrates at the end of a 1000μm core multimode fiber using different PS beads having diameter 50nm, 100 nm and 400 nm. SERS enhancement and signal collection of the fiber was optimized by varying the concentration of beads and hence their packing density. SERS performance of such PS coated fibers were evaluated by studying the signal intensity measured from a monolayer of one of the common Raman active molecules, 2-naphthalenethiol, which can covalently adsorb onto the active end of the fiber. Efficacy of the fiber for real time remote sensing of liquid sample was demonstrated and direction for developing an in vivo biosensing platform is discussed.
Source Title: 2010 Photonics Global Conference, PGC 2010
ISBN: 9781424498826
DOI: 10.1109/PGC.2010.5706009
Appears in Collections:Staff Publications

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