Please use this identifier to cite or link to this item: https://doi.org/10.1089/jpm.2012.0050
Title: Targeted therapy at the end of life in advanced cancer patients
Authors: Soh, T.I.P.
Yuen, Y.-C.
Teo, C.
Lim, S.-W. 
Chan, N.
Wong, A.S.C.
Issue Date: 1-Sep-2012
Citation: Soh, T.I.P., Yuen, Y.-C., Teo, C., Lim, S.-W., Chan, N., Wong, A.S.C. (2012-09-01). Targeted therapy at the end of life in advanced cancer patients. Journal of Palliative Medicine 15 (9) : 991-997. ScholarBank@NUS Repository. https://doi.org/10.1089/jpm.2012.0050
Abstract: Objective: We describe the use of systemic therapy in advanced cancer patients admitted to an acute care hospital, with a focus on targeted therapy. We aim to spotlight the utilization of targeted agents in the last months of life. Methods: Adult patients (N=252) with advanced solid tumors who died as inpatients in the National University Hospital, Singapore, were included in this retrospective study. Patients' demographic and clinical data were extracted from hospital records. Information on systemic therapy was extracted from the time of diagnosis and all other data limited to the last three months before death. Results: 187 adult patients received palliative systemic therapy from the time of diagnosis, of which 125 (66.8%) received it within three months of death. Of patients receiving only nontargeted systemic treatment (n=106), 60 (56.6%) and 26 (24.5%) received it within three months and one month of death respectively. Comparatively, 81 patients received palliative targeted systemic therapy, of which 65 (80.3%) and 40 (49.4%) had treatment within three months and one month of death respectively (p=0.001 and p
Source Title: Journal of Palliative Medicine
URI: http://scholarbank.nus.edu.sg/handle/10635/106412
ISSN: 10966218
DOI: 10.1089/jpm.2012.0050
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