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|Title:||Redistribution of power spectrum of heart rate variability during acute umbilical artery embolism and hypoxemia in late-gestation fetal sheep||Authors:||Li, X.
Fetal heart rate variability
heart rate variability
mean arterial pressure
Power spectral analysis
|Issue Date:||15-Jun-2004||Citation:||Li, X., Tang, D., Zhou, S., Zhou, G., Wang, C., Zhuang, Y., Wu, G., Shen, L. (2004-06-15). Redistribution of power spectrum of heart rate variability during acute umbilical artery embolism and hypoxemia in late-gestation fetal sheep. European Journal of Obstetrics Gynecology and Reproductive Biology 114 (2) : 137-143. ScholarBank@NUS Repository. https://doi.org/10.1016/j.ejogrb.2003.10.009||Abstract:||Objects: Fetal heart rate variability (HRV) is subject to a number of factors, including fetal distress. The aim of this study was to investigate the power spectral distribution of fetal heart rate variability during acute hypoxemia following umbilical artery embolism and to test the hypothesis that the relative proportion of frequency domains in total power of HRV, reflects the changes in HRV during hypoxemia more closely than the absolute values. Methods: Acute hypoxemia was induced in seven catheterized late-gestation fetal sheep by repeated injections of microspheres to cause umbilical artery embolism. The very-low, low-, middle- and high-frequency domains (0-0.025, 0.025-0.125, 0.125-0.20, and 0.20-0.50 cycles/beat, respectively) were determined by power spectral analysis. Results: Umbilical artery embolism induced marked fetal hypoxemia, hypercapnia and acidosis, accompanied by an increase in heart rate and a decrease in arterial blood pressure. These changes were associated with the increase in power over the entire frequency range and in the relative power in the low-frequency range (P||Source Title:||European Journal of Obstetrics Gynecology and Reproductive Biology||URI:||http://scholarbank.nus.edu.sg/handle/10635/106294||ISSN:||03012115||DOI:||10.1016/j.ejogrb.2003.10.009|
|Appears in Collections:||Staff Publications|
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