Please use this identifier to cite or link to this item:
https://scholarbank.nus.edu.sg/handle/10635/106053
DC Field | Value | |
---|---|---|
dc.title | Influence of production variables on the sphericity of melt pellets | |
dc.contributor.author | Heng, P.W.S. | |
dc.contributor.author | Wong, T.W. | |
dc.contributor.author | Chan, L.W. | |
dc.date.accessioned | 2014-10-29T01:54:20Z | |
dc.date.available | 2014-10-29T01:54:20Z | |
dc.date.issued | 2000-03 | |
dc.identifier.citation | Heng, P.W.S., Wong, T.W., Chan, L.W. (2000-03). Influence of production variables on the sphericity of melt pellets. Chemical and Pharmaceutical Bulletin 48 (3) : 420-424. ScholarBank@NUS Repository. | |
dc.identifier.issn | 00092363 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/106053 | |
dc.description.abstract | This paper reports the influence of post-melt impeller speed, post-melt processing time, binder concentration and particle size of bulk material on the sphericity of pellets produced by melt pelletization in a high shear mixer. Lactose was used as the bulk material with polyethylene glycol 3000 as a meltable binder. Time sphericity of pellets was found to be affected by post-melt impeller speed and post-melt processing time. Binder concentration and particle size of bulk material had a lesser effect on pellet sphericity. The melt pelletization process can be divided into two spheronization phases (a fast initial rate, followed by a slower rate). The change in the spheronization rate was associated with time pellet size, porosity and flow pattern of time processing material. The present study established a bi- exponential mathematical model to relate the pellet sphericity with post-melt specific energy consumption. The relationship of pellet sphericity with post- melt specific energy consumption was independent of the effects of the production variables. | |
dc.source | Scopus | |
dc.subject | Energy | |
dc.subject | High shear mixer | |
dc.subject | Melt pelletization | |
dc.subject | Sphericity | |
dc.type | Article | |
dc.contributor.department | PHARMACY | |
dc.description.sourcetitle | Chemical and Pharmaceutical Bulletin | |
dc.description.volume | 48 | |
dc.description.issue | 3 | |
dc.description.page | 420-424 | |
dc.description.coden | CPBTA | |
dc.identifier.isiut | NOT_IN_WOS | |
Appears in Collections: | Staff Publications |
Show simple item record
Files in This Item:
There are no files associated with this item.
Google ScholarTM
Check
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.