Please use this identifier to cite or link to this item:
https://doi.org/10.1002/pds.3516
DC Field | Value | |
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dc.title | Impact of cancer-related fatigue on chemotherapy-induced nausea and vomiting in Asian cancer patients | |
dc.contributor.author | Poon, K.S.H. | |
dc.contributor.author | Un, M.K. | |
dc.contributor.author | Low, X.H. | |
dc.contributor.author | Cheung, Y.T. | |
dc.contributor.author | Yap, K.Y.-L. | |
dc.contributor.author | Chan, A. | |
dc.date.accessioned | 2014-10-29T01:53:55Z | |
dc.date.available | 2014-10-29T01:53:55Z | |
dc.date.issued | 2013-12 | |
dc.identifier.citation | Poon, K.S.H., Un, M.K., Low, X.H., Cheung, Y.T., Yap, K.Y.-L., Chan, A. (2013-12). Impact of cancer-related fatigue on chemotherapy-induced nausea and vomiting in Asian cancer patients. Pharmacoepidemiology and Drug Safety 22 (12) : 1345-1351. ScholarBank@NUS Repository. https://doi.org/10.1002/pds.3516 | |
dc.identifier.issn | 10538569 | |
dc.identifier.uri | http://scholarbank.nus.edu.sg/handle/10635/106022 | |
dc.description.abstract | Introduction: Cancer-related fatigue (CRF) has been suggested to be associated with the occurrence of chemotherapy-induced nausea and vomiting (CINV). This study aims to evaluate the potential of CRF in predicting the occurrence of CINV. Method: This is a prospective, observational study. Recruited patients received moderately to highly emetogenic single-day chemotherapy regimens. On the day of chemotherapy, patients were instructed to provide a score (Likert scale of 0-10) to describe how CRF interfered with his or her ability to engage in daily activities and a score for how severe it was. Patients were then given a standardized 5-day diary to document their CINV events. Results: A total of 473 eligible patients (median age: 55years, interquartile range (IQR): 48-61years) were recruited, with most of the patients diagnosed with gastrointestinal (45%) and breast (37%) cancers. The median score of fatigue interference was 3 (IQR: 0-5). After confounders were adjusted for, patients with low fatigue interference scores (≤3) were more likely to achieve complete protection (no nausea, no vomiting, and no breakthrough antiemetics) of CINV (adjusted odds ratio=1.57, 95%CI [1.05, 2.35], p=0.027). Conclusion: This is the largest study to date to evaluate the association between CRF and CINV. Patients experiencing CRF possessed a higher risk of poor control for CINV. © 2013 John Wiley & Sons, Ltd. | |
dc.description.uri | http://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/pds.3516 | |
dc.source | Scopus | |
dc.subject | Anticancer treatment | |
dc.subject | Anxiety | |
dc.subject | Cancer | |
dc.subject | Chemotherapy | |
dc.subject | Fatigue | |
dc.subject | Nausea and vomiting | |
dc.subject | Pharmacoepidemiology | |
dc.type | Article | |
dc.contributor.department | PHARMACY | |
dc.description.doi | 10.1002/pds.3516 | |
dc.description.sourcetitle | Pharmacoepidemiology and Drug Safety | |
dc.description.volume | 22 | |
dc.description.issue | 12 | |
dc.description.page | 1345-1351 | |
dc.description.coden | PDSAE | |
dc.identifier.isiut | 000327446700013 | |
Appears in Collections: | Staff Publications |
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