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Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/105687
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dc.titleAssessment of powder cohesiveness in spheronization studies
dc.contributor.authorHeng, P.W.S.
dc.contributor.authorWan, L.S.C.
dc.contributor.authorLing, B.L.
dc.date.accessioned2014-10-29T01:49:03Z
dc.date.available2014-10-29T01:49:03Z
dc.date.issued1995-03-14
dc.identifier.citationHeng, P.W.S.,Wan, L.S.C.,Ling, B.L. (1995-03-14). Assessment of powder cohesiveness in spheronization studies. International Journal of Pharmaceutics 116 (1) : 119-123. ScholarBank@NUS Repository.
dc.identifier.issn03785173
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/105687
dc.description.abstractThe effect of water on the cohesiveness of lactose-Avicel and lactose-Emcocel powder formulations was studied. Rod penetration depth and power consumption methods were used to demonstrate the change in the cohesiveness pattern of the moistened powder mass. The results showed that the amount of water necessary for successful spheronization could be ascertained. The two brands of microcrystalline celluloses (MCC) showed differences in their cohesive properties under wet massing and thus, in spheronization, adjustments must be made when one brand is substituted with another. © 1995.
dc.sourceScopus
dc.subjectCohesiveness
dc.subjectMicrocrystalline cellulose
dc.subjectMoistening liquid
dc.subjectPower consumption
dc.subjectRod penetration depth
dc.typeArticle
dc.contributor.departmentPHARMACY
dc.description.sourcetitleInternational Journal of Pharmaceutics
dc.description.volume116
dc.description.issue1
dc.description.page119-123
dc.description.codenIJPHD
dc.identifier.isiutNOT_IN_WOS
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