Please use this identifier to cite or link to this item:
https://doi.org/10.1080/14786410801931629
| Title: | Anti-inflammatory components isolated from Atractylodes macrocephala Koidz | Authors: | Dong, H. He, L. Huang, M. Dong, Y. |
Keywords: | 14-acetoxy-12-α-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol 14-acetoxy-12-senecioyloxytetradeca-2E,8E,10E-trien-4,6-diyn-1-ol Anti-inflammatory effects Atractylenolide I Atractylenolide III Atractylodis macrocephalae |
Issue Date: | 10-Nov-2008 | Citation: | Dong, H., He, L., Huang, M., Dong, Y. (2008-11-10). Anti-inflammatory components isolated from Atractylodes macrocephala Koidz. Natural Product Research 22 (16) : 1418-1427. ScholarBank@NUS Repository. https://doi.org/10.1080/14786410801931629 | Abstract: | The petroleum ether-ether (1:1) extract of Atractylodis macrocephalae was screened by cell membrane chromatography (CMC) and subsequently separated by column chromatography (CC) and high performance liquid chromatography (HPLC). Five components were isolated and identified as atractylenolide III 1, atractylenolide I 2, 14-acetoxy-12-senecioyloxytetradeca-2E,8E,10E-trien-4,6-diyn-1-ol 3, 14-acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol 4 and 14-acetoxy-12-β-methylbutyl-2E,8E,10E-trien-4,6-diyn-1-ol 5 by routine spectrometric methods. The data of 5 and 13C-NMR data of 3 and 4 were reported for the first time. Further in vivo experiments showed that the five components exhibited significant inhibiting effects both on the ear edema induced by xylene and on the peritoneal capillary permeability induced by acetic acid in mice. | Source Title: | Natural Product Research | URI: | http://scholarbank.nus.edu.sg/handle/10635/105652 | ISSN: | 14786419 | DOI: | 10.1080/14786410801931629 |
| Appears in Collections: | Staff Publications |
Show full item record
Files in This Item:
There are no files associated with this item.
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.