Please use this identifier to cite or link to this item:
|Title:||Wilson confidence intervals for the two-sample log-odds-ratio in stratified 2 × 2 contingency tables||Authors:||Brown, B.M.
|Issue Date:||2012||Citation:||Brown, B.M., Suesse, T., Yap, V.B. (2012). Wilson confidence intervals for the two-sample log-odds-ratio in stratified 2 × 2 contingency tables. Communications in Statistics - Theory and Methods 41 (18) : 3355-3370. ScholarBank@NUS Repository. https://doi.org/10.1080/03610926.2011.560779||Abstract:||Large-sample Wilson-type confidence intervals (CIs) are derived for a parameter of interest in many clinical trials situations: the log-odds-ratio, in a two-sample experiment comparing binomial success proportions, say between cases and controls. The methods cover several scenarios: (i) results embedded in a single 2 × 2 contingency table; (ii) a series of K 2 × 2 tables with common parameter; or (iii) K tables, where the parameter may change across tables under the influence of a covariate. The calculations of the Wilson CI require only simple numerical assistance, and for example are easily carried out using Excel. The main competitor, the exact CI, has two disadvantages: It requires burdensome search algorithms for the multi-table case and results in strong over-coverage associated with long confidence intervals. All the application cases are illustrated through a wellknown example. A simulation study then investigates how the Wilson CI performs among several competing methods. The Wilson interval is shortest, except for very large odds ratios, while maintaining coverage similar to Wald-type intervals. An alternative to the Wald CI is the Agresti-Coull CI, calculated from the Wilson and Wald CIs, which has same length as the Wald CI but improved coverage. Copyright © Taylor & Francis Group, LLC.||Source Title:||Communications in Statistics - Theory and Methods||URI:||http://scholarbank.nus.edu.sg/handle/10635/105466||ISSN:||03610926||DOI:||10.1080/03610926.2011.560779|
|Appears in Collections:||Staff Publications|
Show full item record
Files in This Item:
There are no files associated with this item.
checked on Aug 14, 2019
WEB OF SCIENCETM
checked on Aug 14, 2019
checked on Aug 17, 2019
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.