Please use this identifier to cite or link to this item: https://scholarbank.nus.edu.sg/handle/10635/104763
Title: Drug binding to DNA: Observation of the drug-DNA hydrogen-bond-stretching modes of netropsin bound to DNA via raman spectroscopy
Authors: Lee, S.A.
Rupprecht, A.
Chen, Y.Z. 
Issue Date: 1998
Citation: Lee, S.A.,Rupprecht, A.,Chen, Y.Z. (1998). Drug binding to DNA: Observation of the drug-DNA hydrogen-bond-stretching modes of netropsin bound to DNA via raman spectroscopy. Physical Review Letters 80 (10) : 2241-2244. ScholarBank@NUS Repository.
Abstract: Raman scattering and normal mode calculations have been used to study the low frequency vibrations of NaDNA, netropsin, and the NaDNA-netropsin complex. Vibrational modes at about 60 and 180cm-1 are observed from the DNA-netropsin complex but not from either pure DNA or pure netropsin. Theoretical calculations show that these are stretching modes of the hydrogen bonds connecting netropsin to DNA. Identification of these modes in this and other systems may facilitate the study of biomolecule-ligand binding dynamics.
Source Title: Physical Review Letters
URI: http://scholarbank.nus.edu.sg/handle/10635/104763
ISSN: 00319007
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.

Page view(s)

29
checked on Aug 17, 2019

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.