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|Title:||Transcriptional and epigenetic regulations of embryonic stem cells||Authors:||Ng, J.-H.
|Keywords:||Embryonic stem cell
Transcriptional regulatory network
|Issue Date:||1-Dec-2008||Citation:||Ng, J.-H., Heng, J.-C.D., Loh, Y.-H., Ng, H.-H. (2008-12-01). Transcriptional and epigenetic regulations of embryonic stem cells. Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis 647 (1-2) : 52-58. ScholarBank@NUS Repository. https://doi.org/10.1016/j.mrfmmm.2008.08.009||Abstract:||Embryonic stem cells (ESCs) are characterized by their broad developmental potential and the capacity to self-renew. The advent of high-throughput technologies has facilitated genome-wide studies of transcriptional network, resulting in an ever-increasing repertoire of transcription factors implicated in the maintenance of the embryonic stem cell state. While the transcriptional circuitry continues to expand, epigenetic regulation has also gained attention as an important process in stem cell function. Herein, we discuss the recent advancements made in understanding the transcriptional and epigenetic regulations of embryonic stem cells. © 2008.||Source Title:||Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis||URI:||http://scholarbank.nus.edu.sg/handle/10635/102575||ISSN:||00275107||DOI:||10.1016/j.mrfmmm.2008.08.009|
|Appears in Collections:||Staff Publications|
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