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Title: The transcriptional and signalling networks of pluripotency
Authors: Ng, H.-H. 
Surani, M.A.
Issue Date: May-2011
Citation: Ng, H.-H., Surani, M.A. (2011-05). The transcriptional and signalling networks of pluripotency. Nature Cell Biology 13 (5) : 490-496. ScholarBank@NUS Repository.
Abstract: Pluripotency and self-renewal are the hallmarks of embryonic stem cells. This state is maintained by a network of transcription factors and is influenced by specific signalling pathways. Current evidence indicates that multiple pluripotent states can exist in vitro. Here we review the recent advances in studying the transcriptional regulatory networks that define pluripotency, and elaborate on how manipulation of signalling pathways can modulate pluripotent states to varying degrees. © 2011 Macmillan Publishers Limited. All rights reserved.
Source Title: Nature Cell Biology
ISSN: 14657392
DOI: 10.1038/ncb0511-490
Appears in Collections:Staff Publications

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