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|Title:||Quorum quenching and proactive host defense||Authors:||Zhang, L.-H.||Issue Date:||1-May-2003||Citation:||Zhang, L.-H. (2003-05-01). Quorum quenching and proactive host defense. Trends in Plant Science 8 (5) : 238-244. ScholarBank@NUS Repository. https://doi.org/10.1016/S1360-1385(03)00063-3||Abstract:||Both plants and humans have inducible defense mechanisms. This passive defense strategy leaves the host unprotected for a period of time until resistance is activated. Moreover, many bacterial pathogens have evolved cell-cell communication (quorum-sensing) mechanisms to mount population-density-dependent attacks to overwhelm the host's defense responses. Several chemicals and enzymes have been investigated for years for their potential to target the key components of bacterial quorum-sensing systems. These quorum-quenching reagents, which block bacterial cell-cell communications, can disintegrate a bacterial population-density-dependent attack. It has now been shown that a quorum-quenching mechanism can be engineered in plants and might be used as a strategy in controlling bacterial pathogens and to build up a proactive defense barrier.||Source Title:||Trends in Plant Science||URI:||http://scholarbank.nus.edu.sg/handle/10635/102524||ISSN:||13601385||DOI:||10.1016/S1360-1385(03)00063-3|
|Appears in Collections:||Staff Publications|
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