Please use this identifier to cite or link to this item: https://doi.org/10.2741/3047
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dc.titleMethods and protocols for the assessment of protein allergenicity and cross-reactivity
dc.contributor.authorJoo, C.T.
dc.contributor.authorTammi, M.T.
dc.date.accessioned2014-10-27T08:48:45Z
dc.date.available2014-10-27T08:48:45Z
dc.date.issued2008
dc.identifier.citationJoo, C.T., Tammi, M.T. (2008). Methods and protocols for the assessment of protein allergenicity and cross-reactivity. Frontiers in Bioscience 13 (13) : 4882-4888. ScholarBank@NUS Repository. https://doi.org/10.2741/3047
dc.identifier.issn10939946
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/102489
dc.description.abstractAllergy is a prevalent health problem in developed countries. With advances in genomic and proteomic technologies, there is a rapid increase in allergy-related data, including allergen sequences, allergic cross-reactivity, molecular structures, clinical measurements, and atmospheric concentrations. The more and more complex allergy data is fueling the need for advanced ways in information management and analysis. Computational methods and resources are increasingly the driving force in allergy research. For example, allergen-specific databases are important data sources for allergen characterization. T-cell and B-cell epitope prediction tools focus on identifying immunogenic regions on allergenic proteins. Allergenicity and cross-reactivity prediction tools are increasingly being applied to assess the potential allergenicity of proteins. This review provides an introduction to the growing literature in this area, with particular emphasis on recent developments in bioinformatics relevant to the study of allergens.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.2741/3047
dc.sourceScopus
dc.subjectAllergen data
dc.subjectBioinformatics
dc.subjectImmunologic databases
dc.typeReview
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.2741/3047
dc.description.sourcetitleFrontiers in Bioscience
dc.description.volume13
dc.description.issue13
dc.description.page4882-4888
dc.identifier.isiut000255885000127
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