Please use this identifier to cite or link to this item: https://doi.org/10.1111/j.1440-169X.2009.01163.x
Title: Alternative splicing of SMADs in differentiation and tissue homeostasis
Authors: Tao, S.
Sampath, K. 
Keywords: RNA splicing
SMADs
TGF-β/SMAD signalling
Tissue homeostasis
Issue Date: May-2010
Citation: Tao, S., Sampath, K. (2010-05). Alternative splicing of SMADs in differentiation and tissue homeostasis. Development Growth and Differentiation 52 (4) : 335-342. ScholarBank@NUS Repository. https://doi.org/10.1111/j.1440-169X.2009.01163.x
Abstract: Tissue-specific alternate splicing is an important means of regulating gene expression during development. The effector proteins for the transforming growth factor-β signaling pathway, the SMADs, encode distinct isoforms generated via alternate splicing, which appear to have distinct tissue-specific expression profiles and functions. Here, we discuss the roles of various SMAD isoforms, and the consequences of mis-regulation of SMAD splicing in development and tissue homeostasis. © 2010 Japanese Society of Developmental Biologists.
Source Title: Development Growth and Differentiation
URI: http://scholarbank.nus.edu.sg/handle/10635/102401
ISSN: 00121592
DOI: 10.1111/j.1440-169X.2009.01163.x
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