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|Title:||In-silico approaches to multi-target drug discovery computer aided multi-target drug design, multi-target virtual screening||Authors:||Ma, X.H.
|Keywords:||Computer aided dug design
Multi-target drug discovety
|Issue Date:||May-2010||Citation:||Ma, X.H., Shi, Z., Tan, C., Jiang, Y., Go, M.L., Low, B.C., Chen, Y.Z. (2010-05). In-silico approaches to multi-target drug discovery computer aided multi-target drug design, multi-target virtual screening. Pharmaceutical Research 27 (5) : 739-749. ScholarBank@NUS Repository. https://doi.org/10.1007/s11095-010-0065-2||Abstract:||Multi-target drugs against selective multiple targets improve therapeutic efficacy, safety and resistance profiles by collective regulations of a primary therapeutic target together with compensatory elements and resistance activities. Efforts have been made to employ in-silico methods for facilitating the search and design of selective multi-target agents. These methods have shown promising potential in facilitating drug discovery directed at selective multiple targets. © 2010 Springer Science+Business Media, LLC.||Source Title:||Pharmaceutical Research||URI:||http://scholarbank.nus.edu.sg/handle/10635/102336||ISSN:||07248741||DOI:||10.1007/s11095-010-0065-2|
|Appears in Collections:||Staff Publications|
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