Please use this identifier to cite or link to this item: https://doi.org/10.1007/s11095-010-0065-2
Title: In-silico approaches to multi-target drug discovery computer aided multi-target drug design, multi-target virtual screening
Authors: Ma, X.H. 
Shi, Z.
Tan, C.
Jiang, Y.
Go, M.L. 
Low, B.C. 
Chen, Y.Z. 
Keywords: Computer aided dug design
Multi-target
Multi-target drug discovety
Multiple ligands
Virtual screening
Issue Date: May-2010
Citation: Ma, X.H., Shi, Z., Tan, C., Jiang, Y., Go, M.L., Low, B.C., Chen, Y.Z. (2010-05). In-silico approaches to multi-target drug discovery computer aided multi-target drug design, multi-target virtual screening. Pharmaceutical Research 27 (5) : 739-749. ScholarBank@NUS Repository. https://doi.org/10.1007/s11095-010-0065-2
Abstract: Multi-target drugs against selective multiple targets improve therapeutic efficacy, safety and resistance profiles by collective regulations of a primary therapeutic target together with compensatory elements and resistance activities. Efforts have been made to employ in-silico methods for facilitating the search and design of selective multi-target agents. These methods have shown promising potential in facilitating drug discovery directed at selective multiple targets. © 2010 Springer Science+Business Media, LLC.
Source Title: Pharmaceutical Research
URI: http://scholarbank.nus.edu.sg/handle/10635/102336
ISSN: 07248741
DOI: 10.1007/s11095-010-0065-2
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