Please use this identifier to cite or link to this item:
Title: Nitric oxide enhances the capacitance of self-assembled, supported bilayer lipid membranes
Authors: Ye, J.-S. 
Ottova, A.
Tien, H.T.
Sheu, F.-S. 
Keywords: BLMs
Cyclic voltammetry
Membrane capacitance
Nitric oxide
Planar lipid bilayer
Supported bilayer lipid membrane
Issue Date: 2001
Citation: Ye, J.-S., Ottova, A., Tien, H.T., Sheu, F.-S. (2001). Nitric oxide enhances the capacitance of self-assembled, supported bilayer lipid membranes. Electrochemistry Communications 3 (10) : 580-584. ScholarBank@NUS Repository.
Abstract: The effect of nitric oxide (NO) at biologically relevant concentrations on the electrochemical features of the membrane was investigated by cyclic voltammetry (CV) at self-assembled, stainless steel supported lipid bilayer membranes (s-BLMs) using a three-electrode system. The results showed that the membrane capacitance (Cm) of s-BLMs was dramatically enhanced by the presence of increasing NO concentration from 0 to 70 μM. For comparison, fullerene C60 doped s-BLMs (C60@s-BLMs) was also studied. The Cm of C60@s-BLMs increased with NO concentration from 0 to 16 μM and gradually reached a plateau value when NO concentration was over 16 μM. We concluded that (i) NO accumulated inside lipid bilayer increases the Cm of s-BLMs, and (ii) C60 inside s-BLMs changes the dielectric constant of lipid bilayer, thus reducing the effect of NO on the Cm of C60@s-BLMs. This novel self-assembled lipid modified probe provides a simple yet interesting model to study the effect of NO on the electrical conductance of the membrane. © 2001 Elsevier Science B.V. All rights reserved.
Source Title: Electrochemistry Communications
ISSN: 13882481
DOI: 10.1016/S1388-2481(01)00227-2
Appears in Collections:Staff Publications

Show full item record
Files in This Item:
There are no files associated with this item.


checked on Dec 5, 2019


checked on Dec 5, 2019

Page view(s)

checked on Nov 30, 2019

Google ScholarTM



Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.