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|Title:||Mite sensitization among Latina women in New York, where dust-mite allergen levels are typically low||Authors:||Chew, G.L.
|Issue Date:||Jun-2009||Citation:||Chew, G.L., Reardon, A.M., Correa, J.C., Young, M., Acosta, L., Mellins, R., Chew, F.T., Perzanowski, M.S. (2009-06). Mite sensitization among Latina women in New York, where dust-mite allergen levels are typically low. Indoor Air 19 (3) : 193-197. ScholarBank@NUS Repository.||Abstract:||In New York (NY), Latinos often have greater asthma morbidity than other ethnicities, and dust-mite sensitization is common despite low allergen levels. We investigated mite allergen exposure and sensitization in atopic and/or asthmatic women, the majority being Puerto Rican. Women (n = 274) recruited for a birth cohort study were visited postnatally. Dust from their homes was analyzed for mite allergens (Der f 1, Der p 1, and Blo t 5). Serum was analyzed for total and allergen-specific IgE. Thirty-seven percent were sensitized to Dermatophagoides pteronyssinus, 34% to Dermatophagoides farinae, and 21% to Blomia tropicalis. Only 5% of NY homes had levels of Der f 1 >2 μg/g; none had Blo t 5 or Der p 1 above this level. Caribbean or Latin American birthplace (a proxy for childhood exposure) was not associated with mite sensitization. Sensitization to D. pteronyssinus and D. farinae was associated with a report of doctor-diagnosed asthma [Odds ratio (OR) = 3.27, P = 0.003; OR = 2.81, P = 0.010, respectively]; sensitization to any mite was associated with asthma medication use in the past 12 months (OR = 3.12, P = 0.004). These associations held even after adjustment for cockroach, mouse, and cat sensitization. © Blackwell Munksgaard 2009.||Source Title:||Indoor Air||URI:||http://scholarbank.nus.edu.sg/handle/10635/101104||ISSN:||09056947|
|Appears in Collections:||Staff Publications|
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