Please use this identifier to cite or link to this item: https://doi.org/10.1002/dvdy.21477
DC FieldValue
dc.titleLiver-specific expression of p53-negative regulator mdm2 leads to growth retardation and fragile liver in zebrafish
dc.contributor.authorChen, L.-J.
dc.contributor.authorHsu, C.-C.
dc.contributor.authorHong, J.-R.
dc.contributor.authorJou, L.-K.
dc.contributor.authorTseng, H.-C.
dc.contributor.authorWu, J.-L.
dc.contributor.authorLiou, Y.-C.
dc.contributor.authorHer, G.M.
dc.date.accessioned2014-10-27T08:32:42Z
dc.date.available2014-10-27T08:32:42Z
dc.date.issued2008-04
dc.identifier.citationChen, L.-J., Hsu, C.-C., Hong, J.-R., Jou, L.-K., Tseng, H.-C., Wu, J.-L., Liou, Y.-C., Her, G.M. (2008-04). Liver-specific expression of p53-negative regulator mdm2 leads to growth retardation and fragile liver in zebrafish. Developmental Dynamics 237 (4) : 1070-1081. ScholarBank@NUS Repository. https://doi.org/10.1002/dvdy.21477
dc.identifier.issn10588388
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/101025
dc.description.abstractTumorigenesis requires inactivation of the p53 tumor suppressor pathway, likely involving the negative regulator Mdm2 protein. To analyze the possible roles of Mdm2 in oncogenesis and other functions during zebrafish hepatogenesis, we generated transgenic zebrafish by liver-specific Mdm2 over-expression utilizing a fusion between genes encoding GFP and mdm2, GFP
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1002/dvdy.21477
dc.sourceScopus
dc.subjectAgenesis, atrophy
dc.subjectContraction
dc.subjectGFP
dc.subjectHepatogenesis
dc.subjectHypoplasia
dc.subjectLiver degeneration
dc.subjectMdm2
dc.subjectp53
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.1002/dvdy.21477
dc.description.sourcetitleDevelopmental Dynamics
dc.description.volume237
dc.description.issue4
dc.description.page1070-1081
dc.description.codenDEDYE
dc.identifier.isiut000254903700018
Appears in Collections:Staff Publications

Show simple item record
Files in This Item:
There are no files associated with this item.

SCOPUSTM   
Citations

13
checked on Aug 19, 2019

WEB OF SCIENCETM
Citations

13
checked on Jul 10, 2019

Page view(s)

44
checked on Aug 17, 2019

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.