Please use this identifier to cite or link to this item: https://doi.org/10.1016/S0925-4773(01)00400-2
Title: Expression of two novel zebrafish iroquois homologues (ziro1 and ziro5) during early development of axial structures and central nervous system
Authors: Wang, X.
Emelyanov, A.
Sleptsova-Friedrich, I.
Korzh, V.
Gong, Z. 
Keywords: Chordo-neural hinge
Embryos
Floor plate
Genome mapping
Hindbrain
Homeobox
Midbrain
Notochord
Placode
Rhombomere
Issue Date: 2001
Citation: Wang, X., Emelyanov, A., Sleptsova-Friedrich, I., Korzh, V., Gong, Z. (2001). Expression of two novel zebrafish iroquois homologues (ziro1 and ziro5) during early development of axial structures and central nervous system. Mechanisms of Development 105 (1-2) : 191-195. ScholarBank@NUS Repository. https://doi.org/10.1016/S0925-4773(01)00400-2
Abstract: Previously, we reported a zebrafish iroquois gene, ziro3, and its expression during early embryogenesis (Mech. Dev. 87 (1999) 165). In the present study, we have isolated two novel zebrafish iroquois genes, ziro1 and ziro5, homologs of mouse Irx1 and mouse Irx5, respectively. The expression of both genes is initiated in dorsal neuroectoderm and mesoderm during gastrulation. Later, their expression appears in the central nervous system (CNS), excluding the telencephalon and most of the diencephalon. ziro1 expression is complementary to that of ziro3 in the notochord and later in the gut. In contrast, ziro5 expression mostly overlaps with that of ziro3. Interestingly, all three iroquois zebrafish genes are expressed in the notochord while only Irx3 is active in the mouse notochord. Their expression in later stages of embryogenesis was also compared. Copyright © 2001 Elsevier Science Ireland Ltd.
Source Title: Mechanisms of Development
URI: http://scholarbank.nus.edu.sg/handle/10635/100645
ISSN: 09254773
DOI: 10.1016/S0925-4773(01)00400-2
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