Please use this identifier to cite or link to this item: https://doi.org/10.1107/S1744309107034239
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dc.titleCrystallization and preliminary X-ray diffraction analysis of hemextin A: A unique anticoagulant protein from Hemachatus haemachatus venom
dc.contributor.authorBanerjee, Y.
dc.contributor.authorKumar, S.
dc.contributor.authorJobichen, C.
dc.contributor.authorKini, R.M.
dc.date.accessioned2014-10-27T08:25:07Z
dc.date.available2014-10-27T08:25:07Z
dc.date.issued2007-07-28
dc.identifier.citationBanerjee, Y., Kumar, S., Jobichen, C., Kini, R.M. (2007-07-28). Crystallization and preliminary X-ray diffraction analysis of hemextin A: A unique anticoagulant protein from Hemachatus haemachatus venom. Acta Crystallographica Section F: Structural Biology and Crystallization Communications 63 (8) : 701-703. ScholarBank@NUS Repository. https://doi.org/10.1107/S1744309107034239
dc.identifier.issn17443091
dc.identifier.urihttp://scholarbank.nus.edu.sg/handle/10635/100375
dc.description.abstractHemextin A was isolated and purified from African Ringhals cobra (Hemachatus haemachatus). It is a three-finger toxin that specifically inhibits blood coagulation factor VIIa and clot formation and that also interacts with hemextin B to form a unique anticoagulant complex. Hemextin A was crystallized by the hanging-drop vapour-diffusion method by equilibration against 0.2 M ammonium acetate, 0.1 M sodium acetate trihydrate pH 4.6 and 30% PEG 4000 as the precipitating agent. The crystals belong to space group P212 121, with unit-cell parameters a = 49.27, b = 49.51, c = 57.87 Å and two molecules in the asymmetric unit. They diffracted to 1.5 Å resolution at beamline X25 at BNL. © International Union of Crystallography 2007.
dc.description.urihttp://libproxy1.nus.edu.sg/login?url=http://dx.doi.org/10.1107/S1744309107034239
dc.sourceScopus
dc.subjectAnticoagulants
dc.subjectHemextin
dc.subjectSnake-venom toxins
dc.subjectThree-finger toxins
dc.typeArticle
dc.contributor.departmentBIOLOGICAL SCIENCES
dc.description.doi10.1107/S1744309107034239
dc.description.sourcetitleActa Crystallographica Section F: Structural Biology and Crystallization Communications
dc.description.volume63
dc.description.issue8
dc.description.page701-703
dc.identifier.isiut000248441400016
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