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Ultrawide field, distortion-corrected ocular shape estimation with MHz optical coherence tomography (OCT)

Tan, Bingyao
McNabb, Ryan P.
Zheng, Feihui
Ci Sim, Yin
Yao, Xinwen
Kuo, Anthony N.
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Abstract
Ocular deformation may be associated with biomechanical alterations in the structures of the eye, especially the cornea and sclera in conditions such as keratoconus, congenital glaucoma, and pathological myopia. Here, we propose a method to estimate ocular shape using an ultrawide field MHz swept-source optical coherence tomography (SS-OCT) with a Fourier Domain Mode-Locked (FDML) laser and distortion correction of the images. The ocular biometrics for distortion correction was collected by an IOLMaster 700, and localized Gaussian curvature was proposed to quantify the ocular curvature covering a field-of-view up to 65°×62°. We achieved repeatable curvature shape measurements (intraclass coefficient = 0.88 ± 0.06) and demonstrated its applicability in a pilot study with individuals (N = 11) with various degrees of myopia. © 2021 Optical Society of America.
Keywords
Source Title
Biomedical Optics Express
Publisher
The Optical Society
Series/Report No.
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Rights
Attribution 4.0 International
Date
2021-08-23
DOI
10.1364/boe.428430
Type
Article
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