Spontaneous base flipping in DNA and its possible role in methyltransferase binding
Chen, Y.Z. Mohan, V. Griffey, R.H.
Mohan, V.
Griffey, R.H.
Citations
Altmetric:
Alternative Title
Abstract
Base flipping in B-DNA crystal structures and the movement of a flipped base in methyltransferase-DNA crystal structures are studied based on a full atomic level description of bond rotational motions. The effects of restraints from enzyme-distorted DNA backbone on the movement of a flipped base in a number of methyltransferase bound DNA crystal structures are investigated.
Keywords
Source Title
Physical Review E - Statistical Physics, Plasmas, Fluids, and Related Interdisciplinary Topics
Publisher
Series/Report No.
Collections
Rights
Date
2000-07
DOI
10.1103/PhysRevE.62.1133
Type
Article